CAJ | 학술논문

目的：探讨血液病患者合并带状疱疹的临床特征及相关危险因素，以便采取措施减少血液病房患者带状疱疹的发生。方法选择2008年7月－2013年6月血液科6118例住院患者，对其医院感染及发生带状疱疹的临床资料进行回顾性分析，通过单因素分析筛选发生带状疱疹的危险因素，并以多元 logistic回归分析发生带状疱疹的高危因素，探讨控制措施，采用SPSS17．0软件进行统计分析。结果 6118例血液病患者共发生医院感染1109例，感染率18．1％，其中发生带状疱疹57例，发生率0．9％，发生率逐年升高；年龄≥60岁、化疗、合并糖尿病、疾病未缓解、粒细胞缺乏是血液病患者发生带状疱疹的危险因素，多因素分析显示，年龄≥60岁和化疗是血液病患者发生带状疱疹最主要的危险因素（P＜0．05）。结论针对发生带状疱疹的危险因素，采取切实可行的措施，以减少血液病患者带状疱疹的发生。
목적：탐토혈액병환자합병대상포진적림상특정급상관위험인소，이편채취조시감소혈액병방환자대상포진적발생。방법선택2008년7월－2013년6월혈액과6118례주원환자，대기의원감염급발생대상포진적림상자료진행회고성분석，통과단인소분석사선발생대상포진적위험인소，병이다원 logistic회귀분석발생대상포진적고위인소，탐토공제조시，채용SPSS17．0연건진행통계분석。결과 6118례혈액병환자공발생의원감염1109례，감염솔18．1％，기중발생대상포진57례，발생솔0．9％，발생솔축년승고；년령≥60세、화료、합병당뇨병、질병미완해、립세포결핍시혈액병환자발생대상포진적위험인소，다인소분석현시，년령≥60세화화료시혈액병환자발생대상포진최주요적위험인소（P＜0．05）。결론침대발생대상포진적위험인소，채취절실가행적조시，이감소혈액병환자대상포진적발생。
OBJECTIVE To investigate the clinical characteristics and relevant risk factors of herpes zoster (HZ) in patients with hematological diseases so as to take countermeasures to reduce the incidence of HZ in hematology ward .METHODS A retrospective review of 6118 patients in hematology ward from Jul .2008 to Jun .2013 was performed .Clinical data of nosocomial infections and HZ in these patients were retrospectively reviewed .The sin‐gle‐factor analysis was used to screen risk factors of HZ and the multivariate logistic regression analysis to analyze high‐risk factors .The control measures were discussed and the software SPSS17 .0 was used for statistical analy‐sis .RESULTS Of 6118 cases of patients in hematology wards , nosocomial infections occurred in 1109 cases (18 .1% ) ,among which there were 57 cases (0 .9% ) of HZ .The incidence rates of infections were increasing by years .Age over 60 years ,chemotherapy ,complication with diabetes ,disease with no remission ,and neutropenia were the risk factors leading to herpes zoster in hematological patients .The multivariate logistic regression analy‐sis showed that age over 60 years and chemotherapy were the major risk factors (P<0 .05) .CONCLUSION It is necessary to take corresponding countermeasures targeting at risk factors to reduce the incidence of HZ in hematol‐ogy wards .