CAJ | 학술논문

目的：探讨糖尿病并发血源性感染患者的病原学分布和临床特征，以指导临床诊断和治疗。方法回顾性分析2011年10月－2014年5月因发热入院并且血培养呈阳性的150例糖尿病患者临床资料，按照是否为脓毒血症分为脓毒症组42例和非脓毒症组108例，对比两组患者临床指标，采用SPSS 17．0软件进行统计分析。结果150例患者中共42例发生脓毒血症，发生率为28．00％；共检出192株病原菌，以大肠埃希菌为主，共77株占40．1％；脓毒血症组的总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇显著低于非脓毒血症组（ P＜0．05）；两组患者之间的原发感染部位相比差异无统计学意义。结论糖尿病并发血源性感染以大肠埃希菌和葡萄球菌属最为常见，糖尿病并发脓毒症以肺炎克雷伯菌最常见，脓毒症组和非脓毒症组具有不同的临床特征，临床诊治时应引起重视。
목적：탐토당뇨병병발혈원성감염환자적병원학분포화림상특정，이지도림상진단화치료。방법회고성분석2011년10월－2014년5월인발열입원병차혈배양정양성적150례당뇨병환자림상자료，안조시부위농독혈증분위농독증조42례화비농독증조108례，대비량조환자림상지표，채용SPSS 17．0연건진행통계분석。결과150례환자중공42례발생농독혈증，발생솔위28．00％；공검출192주병원균，이대장애희균위주，공77주점40．1％；농독혈증조적총담고순、고밀도지단백담고순、저밀도지단백담고순현저저우비농독혈증조（ P＜0．05）；량조환자지간적원발감염부위상비차이무통계학의의。결론당뇨병병발혈원성감염이대장애희균화포도구균속최위상견，당뇨병병발농독증이폐염극뢰백균최상견，농독증조화비농독증조구유불동적림상특정，림상진치시응인기중시。
OBJECTIVE To explore the etiology distribution and clinical characteristics of blood‐borne infections in patients with diabetes mellitus so as to guide the clinical diagnosis and treatment .METHODS The clinical data of 150 diabetic patients who were hospitalized because of fever and presented to be positive in blood culture from Oct . 2011 to May 2014 were retrospectively analyzed .They were divided into sepsis group with 42 cases and non‐sepsis group with 108 cases .The clinical indexes between the two groups were compared .All data were analyzed by SPSS 17 .0 software .RESULTS A total of 42 cases occurred sepsis in the all 150 cases of blood‐borne infection pa‐tients ,and the infection rate was 28 .00% .Generally 192 strains of pathogens were detected . Escherichia coli with 77 strains dominated the majority ,accounting for 40 .1% .Total cholesterol ,high density lipoprotein choles‐terol ,low density lipoprotein cholesterol was significantly lower in the sepsis group than the non‐sepsis group (P<0 .05) .The primary infection sites were almost similar in the two groups and the differences were not signifi‐cant .CONCLUSION Escherichia coli and Staphylococcus aureus are the most common pathogenic bacteria in pa‐tients with diabetes combined with blood‐borne infection . K lebsiella pneumonia is the most common in diabetes combined with sepsis .Sepsis group has different clinical characteristics with non‐sepsis group so special attention must be paid in clinical diagnosis and treatment .