CAJ | 학술논문

目的：探讨盐酸多奈哌齐治疗老年痴呆的临床探析。方法选取2013年11月到2014年12月我院接诊的42例老年痴呆患者，随机分为两组，实验组22例和对照组20例，对照组给予常规治疗，实验组在对照组的基础上给予盐酸多奈哌齐，观察两组患者的治疗效果。结果实验组患者的简易智能精神状态检查量表（MMSE）评分、日常生活能力量表（ADL）评分及不良反应的发生率明显优于对照组，差异显著，有统计学意义（P<0.05）。结论盐酸多奈哌齐治疗老年痴呆的效果显著，有效改善患者的精神状态，提高患者的日常生活能力，值得临床推广。
목적：탐토염산다내고제치료노년치태적림상탐석。방법선취2013년11월도2014년12월아원접진적42례노년치태환자，수궤분위량조，실험조22례화대조조20례，대조조급여상규치료，실험조재대조조적기출상급여염산다내고제，관찰량조환자적치료효과。결과실험조환자적간역지능정신상태검사량표（MMSE）평분、일상생활능역량표（ADL）평분급불량반응적발생솔명현우우대조조，차이현저，유통계학의의（P<0.05）。결론염산다내고제치료노년치태적효과현저，유효개선환자적정신상태，제고환자적일상생활능력，치득림상추엄。
Objective To study the clinical analysis of senile dementia on donepezil HCL treatment. Methods To divide the 42 cases patients into control group (22 cases)and experimental group(20 cases). The patients’cases were chosen from November 2013 to December 2014,the control group adopted conventional treatment,the experimental group adopted the basis of the control group combine with donepezil HCL,to observe the two groups’ therapeutic effect. Results The date of experimental group patients from simple intel igence scale for mental state examination score(MMSE),daily life ability scale score(ADL)and the incidence of adverse reaction was better than control group,it was in a high treatment efficiency and obvious difference and the statistical y significant(P< 0.05). Conclusion Donepezil HCL treatment has significantly effectively on the patients' mental state and the ability of the patients' daily life. It is widely used in clinical promotion.