包头医学院学报
包頭醫學院學報
포두의학원학보
JOURNAL OF BAOTOU MEDICAL COLLEGE
2015年
4期
18-19
,共2页
缺血性脑卒中%甲硫腺苷磷酸化酶%基因表达
缺血性腦卒中%甲硫腺苷燐痠化酶%基因錶達
결혈성뇌졸중%갑류선감린산화매%기인표체
Ischemic Stroke%Methylthioadenonine phosphorylase%Gene expression
目的:研究甲硫腺苷磷酸化酶(methylthioadenonine phosphorylase,MTAP)基因在缺血性脑卒中患者中的表达,探讨MTAP基因与缺血性脑卒中发病的关系。方法:采用聚合酶链式反应( PCR)方法,检测并比较50例缺血性脑卒中患者和50例对照组人群 MTAP基因的表达情况,分析MTAP表达与缺血性脑卒中的相关性。结果:MTAP基因在缺血性脑卒中患者与正常对照组比较,差异无统计学意义( P >0.05)。结论:缺血性脑卒中的发病机制可能与MTAP基因表达无关。
目的:研究甲硫腺苷燐痠化酶(methylthioadenonine phosphorylase,MTAP)基因在缺血性腦卒中患者中的錶達,探討MTAP基因與缺血性腦卒中髮病的關繫。方法:採用聚閤酶鏈式反應( PCR)方法,檢測併比較50例缺血性腦卒中患者和50例對照組人群 MTAP基因的錶達情況,分析MTAP錶達與缺血性腦卒中的相關性。結果:MTAP基因在缺血性腦卒中患者與正常對照組比較,差異無統計學意義( P >0.05)。結論:缺血性腦卒中的髮病機製可能與MTAP基因錶達無關。
목적:연구갑류선감린산화매(methylthioadenonine phosphorylase,MTAP)기인재결혈성뇌졸중환자중적표체,탐토MTAP기인여결혈성뇌졸중발병적관계。방법:채용취합매련식반응( PCR)방법,검측병비교50례결혈성뇌졸중환자화50례대조조인군 MTAP기인적표체정황,분석MTAP표체여결혈성뇌졸중적상관성。결과:MTAP기인재결혈성뇌졸중환자여정상대조조비교,차이무통계학의의( P >0.05)。결론:결혈성뇌졸중적발병궤제가능여MTAP기인표체무관。
Objective:To explore the expression of methylthioadenonine phosphorylase ( MTAP) gene in patients with ischemic stroke and the relationship between MTAP gene and the pathogenesis of ischemic stroke.Methods:The expression of MTAP gene in 50 cases of ischemic stroke and 50 cases in the control group was detected and compared by polymerase chain reaction ( PCR) , analyzing the correlation between the expression of MTAP gene and ischemic stroke.Results:There was no significant difference in MTAP gene between patients with ischemic stroke and patients in the control group( P >0.05).Conclusions:The pathogenesis of ischemic stroke may have nothing to do with the expression of MTAP gene.