西部中医药
西部中醫藥
서부중의약
GANSU JOURNAL OF TRADITIONAL CHINESE MEDICINE
2015年
4期
111-113
,共3页
脑小血管病%非痴呆血管性认知功能损害%补脑膏%尼莫地平
腦小血管病%非癡呆血管性認知功能損害%補腦膏%尼莫地平
뇌소혈관병%비치태혈관성인지공능손해%보뇌고%니막지평
cerebral small vessel disease%vascular cognitive impairment-no dementia%Bu Nao Gao%nimodipine
目的：观察补脑膏联合尼莫地平治疗脑小血管病(CSVD)伴发非痴呆血管性认知功能损害(VCI-ND)的临床疗效。方法：将80例符合诊断标准的患者随机分为对照组、治疗组各40例。2组均口服尼莫地平，观察组同时口服补脑膏，2组连续治疗12周，比较治疗前后蒙特利尔认知评估量表(MoCA)评分。结果：MoCA评分2组治疗后均明显升高(P＜0.05)，观察组升高更明显(P＜0.05)。结论：补脑膏联合尼莫地平治疗CSVD伴发VCIND患者，其疗效优于单独应用尼莫地平治疗者。
目的：觀察補腦膏聯閤尼莫地平治療腦小血管病(CSVD)伴髮非癡呆血管性認知功能損害(VCI-ND)的臨床療效。方法：將80例符閤診斷標準的患者隨機分為對照組、治療組各40例。2組均口服尼莫地平，觀察組同時口服補腦膏，2組連續治療12週，比較治療前後矇特利爾認知評估量錶(MoCA)評分。結果：MoCA評分2組治療後均明顯升高(P＜0.05)，觀察組升高更明顯(P＜0.05)。結論：補腦膏聯閤尼莫地平治療CSVD伴髮VCIND患者，其療效優于單獨應用尼莫地平治療者。
목적：관찰보뇌고연합니막지평치료뇌소혈관병(CSVD)반발비치태혈관성인지공능손해(VCI-ND)적림상료효。방법：장80례부합진단표준적환자수궤분위대조조、치료조각40례。2조균구복니막지평，관찰조동시구복보뇌고，2조련속치료12주，비교치료전후몽특리이인지평고량표(MoCA)평분。결과：MoCA평분2조치료후균명현승고(P＜0.05)，관찰조승고경명현(P＜0.05)。결론：보뇌고연합니막지평치료CSVD반발VCIND환자，기료효우우단독응용니막지평치료자。
Objective: To observe therapeutic effect ofBuNaoGaoand nimodipine in the treatment of cerebral small vessel disease (CSVD) with vascular cognitive impairment-no dementia(VCI-ND). Methods: Totally 80 pa-tients who met the diagnostic standard were randomly divided into the control group and the treatment group with 40 cases in each. Nimodipines was orally given to the patients in both groups, andBuNaoGaowas used only in the treat-ment group for 12 weeks consecutively. The scores of Montreal Cognitive Assessment (MoCA) before and after treatment were compared. Results: Scores of MoCA increased obviously in both groups (P<0.05), the improvement of the treatment group was more obvious (P<0.05). Conclusion: The clinical efficacy ofBuNaoGaocombined with nimodipine in the treatment of CSVD with VCI-ND is superior to that of nimodipine alone.
