CAJ | 학술논문

通过动物实验对发酵方竹笋对蒙脱石散诱导小鼠便秘的预防效果进行了研究．建立便秘动物模型，观察饲喂发酵方竹笋对便秘小鼠的影响．结果显示发酵方竹笋喂养组小鼠的体质量变化接近正常小鼠，高于对照组小鼠．发酵方竹笋喂养组小鼠排出首粒黑便的时间（104 min）低于对照组（185 min）和未发酵方竹笋喂养组（122 min），高于正常组（68 min）和比沙可啶治疗组（90 min）．活性炭在发酵方竹笋喂养组小鼠（68.7％）小肠中的推进率也高于对照组（38.3％）和未发酵方竹笋喂养组（50.4％），低于正常组（98.3％）和比沙可啶治疗组（79.3％）．发酵方竹笋喂养组小鼠血清的胃动素（MTL）、内皮素1（ET‐1）、血管活性肠肽（VIP）和乙酰胆碱酯酶（AchE）水平也显著高于对照组和方竹笋喂养组，低于正常组和比沙可啶治疗组．通过显微镜观察发现，发酵方竹笋纤维品质比未发酵方竹笋更好，有利于预防便秘．发酵方竹笋是一种具有良好抑制便秘作用的健康食品．
통과동물실험대발효방죽순대몽탈석산유도소서편비적예방효과진행료연구．건립편비동물모형，관찰사위발효방죽순대편비소서적영향．결과현시발효방죽순위양조소서적체질량변화접근정상소서，고우대조조소서．발효방죽순위양조소서배출수립흑편적시간（104 min）저우대조조（185 min）화미발효방죽순위양조（122 min），고우정상조（68 min）화비사가정치료조（90 min）．활성탄재발효방죽순위양조소서（68.7％）소장중적추진솔야고우대조조（38.3％）화미발효방죽순위양조（50.4％），저우정상조（98.3％）화비사가정치료조（79.3％）．발효방죽순위양조소서혈청적위동소（MTL）、내피소1（ET‐1）、혈관활성장태（VIP）화을선담감지매（AchE）수평야현저고우대조조화방죽순위양조，저우정상조화비사가정치료조．통과현미경관찰발현，발효방죽순섬유품질비미발효방죽순경호，유리우예방편비．발효방죽순시일충구유량호억제편비작용적건강식품．
This study aims to determining the preventive effects of fermented Chimonobambusa quadrangu‐laris shoot (FCQS) on Montmorillonite powder induced constipation through the animal experiments .The influence of FCQS on constipation mice has beenassessed by buildingof constipation animal model .The re‐sults show that the body weight changes of FCQS fed mice were close to the normal mice ,and the body weights were higher than the control mice .The time for first black stool defecation of FCQS fed group (104min) is lower than control group (185min) and unfermented Chimonobambusa quadrangularis shoot (CQS ) fed group (122min ) , but higher than the normal group (68min ) and bisacodyl treated group (90min) .The intestinal transit of FCQS fed group (68 .7% ) is higher than the control group (38 .3% ) and CQS fed group (50 .4% ) ,and is lower than normal group (98 .3% ) and bisacodyl treated group (79 .3% ) . The serum levels of MTL (motilin) ,ET‐1 (endothelin‐1) ,VIP (vasoactive intestinal peptide) and AchE (acetylcholinesterase)arealso higher than control group and CQS fed group ,but lower than normal group and bisacodyl treated group .The fiber quality of FCQS is better than that of CQS through microscopic ex‐amination .FCQS is an healthy food which exhibits goodinhibitory effect on constipation .