CAJ | 학술논문

目的：探讨人工关节置换后医院假体周围感染的临床表现、危险因素和治疗疗效，以早期采取有效措施降低感染率。方法回顾性分析2006年1月－2012年1月行人工关节置换术患者315例，对其中假体周围感染18例患者从临床表现、危险因素和治疗效果进行总结分析，采用SPSS 16．0软件进行统计分析。结果假体周围感染临床表现为体温升高、关节周围红肿热痛、功能障碍等；其中糖尿病、免疫学疾病、激素使用史、手术时间、抗菌药物未应用是并发革兰阳性菌感染相关因素，也是独立危险因素（ P＜0．05）；经过抗感染治疗后，治愈16例占88．89％、好转2例占11．11％，治疗前后在Harris评分、VAS评分、白细胞计数、C‐反应蛋白、血沉、中性粒细胞计数等有明显的改善（P＜0．05）。结论人工关节置换后假体周围感染临床症状明显，多与患者自身疾病有关，经治疗后预后较好。
목적：탐토인공관절치환후의원가체주위감염적림상표현、위험인소화치료료효，이조기채취유효조시강저감염솔。방법회고성분석2006년1월－2012년1월행인공관절치환술환자315례，대기중가체주위감염18례환자종림상표현、위험인소화치료효과진행총결분석，채용SPSS 16．0연건진행통계분석。결과가체주위감염림상표현위체온승고、관절주위홍종열통、공능장애등；기중당뇨병、면역학질병、격소사용사、수술시간、항균약물미응용시병발혁란양성균감염상관인소，야시독립위험인소（ P＜0．05）；경과항감염치료후，치유16례점88．89％、호전2례점11．11％，치료전후재Harris평분、VAS평분、백세포계수、C‐반응단백、혈침、중성립세포계수등유명현적개선（P＜0．05）。결론인공관절치환후가체주위감염림상증상명현，다여환자자신질병유관，경치료후예후교호。
OBJECTIVE To investigate clinical manifestations ,risk factors and treatment efficacy for prosthetic joint infections after artificial joint replacement so as to take early effective measures to reduce infection rates . METHODS A retrospective analysis was conducted on 315 patients undergoing artificial joint replacement from Jan .2006 to Jan .2012 ,among which 18 patients with prosthetic joint infections were summarized and analyzed for clinical manifestations ,risk factors and treatment efficacy .The software SPSS16 .0 was used for statistical a‐nalysis .RESULTS The clinical manifestations of prosthetic joint infections included fever ,redness and swelling a‐round the joints ,and dysfunction .diabetes ,immunological disorders ,history of hormone use ,operation time , abolishment of antimicrobial agents were related factors for concurrent gram‐positive bacterial infections ,and also independent risk factors (P< 0 .05) .After anti‐infection treatment ,16 patients were cured ,accounting for 88 .89% ,2 improved ,accounting for 11 .11% .There was significant improvement in the Harris score ,VAS score ,white blood cell count ,C‐reactive protein ,erythrocyte sedimentation rate and neutrophil count after treat‐ment (P<0 .05) .CONCLUSION The clinical symptoms of prosthetic joint infections after artificial joint replace‐ment were significant and mainly related with the patients underlying diseases ,while the prognosis was well after treatment .