CAJ | 학술논문

目的：探讨妇科恶性肿瘤切除术化疗后淋巴囊肿发生感染的临床诊治，为其有效治疗提供参考依据。方法选取2010年6月－2013年10月收治112例妇科恶性肿瘤切除术后化疗患者为研究对象，将其随机分为观察组和对照组，各56例；对照组患者给予盆腔淋巴结切除术及C E F化疗方案，观察组在对照组治疗基础上给予粒细胞集落刺激因子（G‐CSF）治疗，两组患者术后均给与静脉注射常规抗菌药物；分析患者淋巴囊肿并发感染的相关因素，比较两组患者淋巴囊肿的发生率、感染率及治疗效果。结果淋巴囊肿发生感染的概率随着患者血红蛋白（Hb）和中性粒细胞（ANC ）的降低及年龄的增高而增高；观察组和对照组淋巴囊肿的发生率分别为44．64％和46．43％，差异无统计学意义，观察组患者的感染率为14．29％，明显低于对照组患者的41．07％，两组比较差异有统计学意义（P＜0．05）。结论妇科恶性肿瘤切除术化疗后淋巴囊肿并发感染的概率与贫血和中性粒细胞（ANC）的降低以及年龄相关，抗菌药物辅以G‐CSF治疗，可有效降低妇科恶性肿瘤切除术化疗后淋巴囊肿的感染率，值得临床推广使用。
목적：탐토부과악성종류절제술화료후림파낭종발생감염적림상진치，위기유효치료제공삼고의거。방법선취2010년6월－2013년10월수치112례부과악성종류절제술후화료환자위연구대상，장기수궤분위관찰조화대조조，각56례；대조조환자급여분강림파결절제술급C E F화료방안，관찰조재대조조치료기출상급여립세포집락자격인자（G‐CSF）치료，량조환자술후균급여정맥주사상규항균약물；분석환자림파낭종병발감염적상관인소，비교량조환자림파낭종적발생솔、감염솔급치료효과。결과림파낭종발생감염적개솔수착환자혈홍단백（Hb）화중성립세포（ANC ）적강저급년령적증고이증고；관찰조화대조조림파낭종적발생솔분별위44．64％화46．43％，차이무통계학의의，관찰조환자적감염솔위14．29％，명현저우대조조환자적41．07％，량조비교차이유통계학의의（P＜0．05）。결론부과악성종류절제술화료후림파낭종병발감염적개솔여빈혈화중성립세포（ANC）적강저이급년령상관，항균약물보이G‐CSF치료，가유효강저부과악성종류절제술화료후림파낭종적감염솔，치득림상추엄사용。
OBJECTIVE To study the clinical diagnosis and treatment of lymphatic cyst complicated with infections in gynecological malignancies resection patients after chemotherapy so as to provide guidance for effective treat‐ment .METHODS A total of 112 gynecological malignancies resection patients who underwent the chemotherapy from Jun 2010 to Oct 2013 were recruited as the study objects and randomly divided into the observation group and the control group ,with 56 cases in each .The control group was treated with pelvic lymphadenectomy and CEF chemotherapy regimens ,while the observation group was given the additional granulocyte colony stimulating factor (G‐CSF) therapy based on the treatment of the control group ;both groups were given the intravenous injection of conventional antibiotics after the surgeries .The related factors for the lymphatic cyst complicated with infections were analyzed ,and the incidence of lymphatic cyst ,infection rate ,and curative effect were observed and compared between the two groups of patients .RESULTS The incidence of lymphatic cyst complicated with infections was in‐creased with the reduction of levels of hemoglobin (Hb) and neutrophils as well as with the increase of age ;the in‐cidence rate of lymphatic cyst was 44 .64% in the observation group ,46 .43% in the control group ,and there was no statistically significant difference .The infection rate of the observation group was 14 .29% ,significantly lower than 41 .07% of the control group ,and there was statistically significant difference between the two groups (P<0 .05) .CONCLUSION The incidence of lymphatic cyst complicated with infections in the gynecological malignan‐cies resection patients undergoing postoperative chemotherapy is associated with the anemia and reduction of neu‐trophils as well as the age;the antibiotics therapy supplemented by G‐CSF can effectively reduce the incidence of lymphatic cyst ,and it is worthy to be promoted in the hospital .