CAJ | 학술논문

目的：探讨外阴阴道假丝酵母菌感染临床特点以及对常用抗菌药物的耐药性，为临床诊断和及时治疗提供依据。方法检测分析医院2011年8月－2013年8月15000例女性患者外阴阴道送检分泌物标本分离出的假丝酵母菌属，鉴定所得标本的菌种属性，分析耐药性，数据采用SPSS 14．0软件进行统计分析。结果15000份标本进行检测，检测出1980份有假丝酵母菌属的感染，检出率为13．2％，其中以白色假丝酵母菌为主，共1415株占71．5％；耐药率最高的是伊曲康唑，耐药率达28．88％，氟康唑为10．44％、伏立康唑为11．52％，但对于两性霉素B以及氟胞嘧啶几乎全部敏感。结论女性外阴阴道的假丝酵母菌属感染以白色假丝酵母菌感染为主，且不同药物有不同的耐药程度，因此要加强临床对于假丝酵母菌属的检测，从而更好的指导临床准确及时的治疗。
목적：탐토외음음도가사효모균감염림상특점이급대상용항균약물적내약성，위림상진단화급시치료제공의거。방법검측분석의원2011년8월－2013년8월15000례녀성환자외음음도송검분비물표본분리출적가사효모균속，감정소득표본적균충속성，분석내약성，수거채용SPSS 14．0연건진행통계분석。결과15000빈표본진행검측，검측출1980빈유가사효모균속적감염，검출솔위13．2％，기중이백색가사효모균위주，공1415주점71．5％；내약솔최고적시이곡강서，내약솔체28．88％，불강서위10．44％、복립강서위11．52％，단대우량성매소B이급불포밀정궤호전부민감。결론녀성외음음도적가사효모균속감염이백색가사효모균감염위주，차불동약물유불동적내약정도，인차요가강림상대우가사효모균속적검측，종이경호적지도림상준학급시적치료。
OBJECTIVE To discuss the clinical features of vulvovaginal infections of Candida and drug resistance to common antibiotics ,so as to provide the basis for clinical diagnosis and timely treatment .METHODS The Candi‐da isolated from secretion samples of 15 000 cases of patients from Aug .2011 to Aug .2013 were detected .The property of the strains was identified and the drug resistance was analyzed .All data were statistically analyzed by SPSS 14 .0 software .RESULTS Totally 15 000 samples were detected by bacteriological testing ,and 1980 samples were found to be infected by Candida ,with the detection rate of 13 .2% .Among them ,Candida albicans with 1 415 strains dominated by 71 .5% .The drug resistant rate of Candida to itraconazole was the highest of 28 .88%and to fluconazole ,it was 10 .44% ,to voriconazole 11 .52% .almost all were sensitive to Amphotericin B and 5‐flucytosine .CONCLUSION C .albicans are the main bacteria infected by female vulva and vagina .And different drugs have different levels of drug resistance ,so we need to strengthen the clinical test for Candida to better guide clinical accurate and timely treatment .