中华医院感染学杂志
中華醫院感染學雜誌
중화의원감염학잡지
Chinese Journal of Nosocomiology
2015年
7期
1616-1617,1625
,共3页
开颅手术%腰穿刺%颅内感染%作用
開顱手術%腰穿刺%顱內感染%作用
개로수술%요천자%로내감염%작용
Craniotomy%Conventional lumbar puncture%Intracranial infection%Effect
目的：研究常规腰穿对开颅手术后颅内感染患者的防治作用，指导临床防治开颅手术患者颅内感染的防治。方法选取符合开颅手术颅内感染诊断标准的患者44例，采用常规抗菌药物治疗的患者18例为对照组；在常规治疗的基础上每天行常规腰穿鞘内注射抗菌药物的26例患者为腰穿组，对比两组患者临床指标，采用Excel进行分析。结果腰穿组患者颅内感染治愈25例治愈率为96．15％，对照组患者治愈16例治愈率为88．89％，腰穿组患者的治愈率稍高于对照组患者，但差异无统计学意义；腰穿组和对照组患者在治疗后体温、脑脊液蛋白含量、葡萄糖含量及脑脊液中白细胞个数与治疗前相比，差异均有统计学意义（ P＜0．05）；腰穿组26例患者，部分患者在感染治愈后有腰痛症状，但均能耐受；对照组患者无此症状发生。结论常规腰穿对于防治开颅手术后颅内感染的治愈率高、疗效好、临床有效治疗时间短，不良反应能够耐受，因此应作为临床常用的控制和治疗开颅手术后颅内感染的常规手段进行推广。
目的：研究常規腰穿對開顱手術後顱內感染患者的防治作用，指導臨床防治開顱手術患者顱內感染的防治。方法選取符閤開顱手術顱內感染診斷標準的患者44例，採用常規抗菌藥物治療的患者18例為對照組；在常規治療的基礎上每天行常規腰穿鞘內註射抗菌藥物的26例患者為腰穿組，對比兩組患者臨床指標，採用Excel進行分析。結果腰穿組患者顱內感染治愈25例治愈率為96．15％，對照組患者治愈16例治愈率為88．89％，腰穿組患者的治愈率稍高于對照組患者，但差異無統計學意義；腰穿組和對照組患者在治療後體溫、腦脊液蛋白含量、葡萄糖含量及腦脊液中白細胞箇數與治療前相比，差異均有統計學意義（ P＜0．05）；腰穿組26例患者，部分患者在感染治愈後有腰痛癥狀，但均能耐受；對照組患者無此癥狀髮生。結論常規腰穿對于防治開顱手術後顱內感染的治愈率高、療效好、臨床有效治療時間短，不良反應能夠耐受，因此應作為臨床常用的控製和治療開顱手術後顱內感染的常規手段進行推廣。
목적：연구상규요천대개로수술후로내감염환자적방치작용，지도림상방치개로수술환자로내감염적방치。방법선취부합개로수술로내감염진단표준적환자44례，채용상규항균약물치료적환자18례위대조조；재상규치료적기출상매천행상규요천초내주사항균약물적26례환자위요천조，대비량조환자림상지표，채용Excel진행분석。결과요천조환자로내감염치유25례치유솔위96．15％，대조조환자치유16례치유솔위88．89％，요천조환자적치유솔초고우대조조환자，단차이무통계학의의；요천조화대조조환자재치료후체온、뇌척액단백함량、포도당함량급뇌척액중백세포개수여치료전상비，차이균유통계학의의（ P＜0．05）；요천조26례환자，부분환자재감염치유후유요통증상，단균능내수；대조조환자무차증상발생。결론상규요천대우방치개로수술후로내감염적치유솔고、료효호、림상유효치료시간단，불량반응능구내수，인차응작위림상상용적공제화치료개로수술후로내감염적상규수단진행추엄。
OBJECTIVE To investigate the prevention effects of conventional lumbar puncture in patients with in‐tracranial infections after craniotomy operation ,so as to guide prevention and treatment of intracranial infections after surgical operation .METHODS Totally 44 patients who met the diagnostic criteria of intracranial infections af‐ter operation were chosen .A total of 18 patients with conventional antimicrobial therapy were chosen as control group .On the basis of routine treatment ,26 patients who were treated with daily routine lumbar puncture to re‐lease the infected cerebrospinal fluid and intrathecal injection of antibiotics were regarded as lumbar puncture group .The clinical indexes of the two groups were compared and the results were statistically analyzed by Excel . RESULTS In the lumbar puncture group ,totally 25 infected cases were cured and the curative rate was 96 .15% . While there were 16 cases in the control group were cured with the curative rate of 88 .89% .The curative rate in the lumbar puncture group was slightly higher than that of the control group but the differences were not signifi‐cant .The body temperature ,protein level in cerebrospinal fluid ,the level of glucose ,and the number of leukocyte in cerebrospinal fluid were compared between the two groups before and after the treatment .The differences were significant (P<0 .05) .Some patients in the lumbar puncture group appeared low back pain but the pain can be tolerated .No similar symptoms appeared in the control group .CONCLUSION The conventional puncture used to prevent and cure intracranial infections has high curative rate ,good efficacy and short clinical curing time and tol‐erant adverse reactions therefore can be treated as routine method in controlling and curing intracranial infections after craniotomy operation promotion .
