中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2015年
11期
1678-1682
,共5页
沈悦%马海英%张彦升%王娟%时炳正
瀋悅%馬海英%張彥升%王娟%時炳正
침열%마해영%장언승%왕연%시병정
组织构建%组织工程%单侧完全性唇腭裂%单侧牙槽嵴裂%锥形束CT%三维测量%颅面形态%正畸矫治%牙槽嵴植骨%稳定性
組織構建%組織工程%單側完全性脣腭裂%單側牙槽嵴裂%錐形束CT%三維測量%顱麵形態%正畸矯治%牙槽嵴植骨%穩定性
조직구건%조직공정%단측완전성진악렬%단측아조척렬%추형속CT%삼유측량%로면형태%정기교치%아조척식골%은정성
Cleft Palate%Cleft Lip%Alveolar Process%Bone Transplantation
背景:部分唇腭裂患者在9-10岁(尖牙牙根发育1/2-2/3)接受植骨后,矫治效果不能保持;且7-10岁患者植骨前后的治疗程序目前尚不统一。锥形束 CT 可在不破坏正常组织结构的前提下精确反映组织的微细结构,并通过相配套的计算机软件获得相关测量数据。目的:利用锥形束CT测量结果,比较不同顺次的正畸联合牙槽嵴裂植骨治疗单侧完全性唇腭裂的疗效。方法:选择2012至2013年就诊于沧州市人民医院的单侧完全性唇腭裂患者60名,分为3组,各20例。A组患者自体髂骨移植修复牙槽嵴裂植骨治疗后佩戴保持器保持3个月行正畸治疗;B组患者正畸治疗后即刻行自体髂骨移植修复牙槽嵴裂植骨治疗并后期佩戴保持器3个月;C组患者正畸治疗后佩戴保持器3个月后行自体髂骨移植修复牙槽嵴裂植骨治疗,植骨治疗完成后保持器保持3个月。结果与结论:锥形束CT结果显示,C组患者蝶鞍点-鼻根点-上齿槽座点角(SNA)、蝶鞍点-鼻根点-下齿槽座点角(SNB)、上齿槽座点-鼻根点-下齿槽座点角(ANB)、上中切牙切缘与鼻根点-上齿槽座点连线的交角(U1/NA)和U1/NA(L1/NB)与A组差异有显著性意义(P <0.01);B组患者的SNB、L1/NB较A组明显增大(P<0.05);C组与B组比较,SNB、U1/NA明显减小,SNA、L1/NB明显增大(P <0.05)。提示单侧完全性唇腭裂患者牙槽嵴植骨治疗前、治疗后正畸治疗效果明显优于单纯治疗前或治疗后正畸治疗,并有利于上颌骨矫正后的稳定性。
揹景:部分脣腭裂患者在9-10歲(尖牙牙根髮育1/2-2/3)接受植骨後,矯治效果不能保持;且7-10歲患者植骨前後的治療程序目前尚不統一。錐形束 CT 可在不破壞正常組織結構的前提下精確反映組織的微細結構,併通過相配套的計算機軟件穫得相關測量數據。目的:利用錐形束CT測量結果,比較不同順次的正畸聯閤牙槽嵴裂植骨治療單側完全性脣腭裂的療效。方法:選擇2012至2013年就診于滄州市人民醫院的單側完全性脣腭裂患者60名,分為3組,各20例。A組患者自體髂骨移植脩複牙槽嵴裂植骨治療後珮戴保持器保持3箇月行正畸治療;B組患者正畸治療後即刻行自體髂骨移植脩複牙槽嵴裂植骨治療併後期珮戴保持器3箇月;C組患者正畸治療後珮戴保持器3箇月後行自體髂骨移植脩複牙槽嵴裂植骨治療,植骨治療完成後保持器保持3箇月。結果與結論:錐形束CT結果顯示,C組患者蝶鞍點-鼻根點-上齒槽座點角(SNA)、蝶鞍點-鼻根點-下齒槽座點角(SNB)、上齒槽座點-鼻根點-下齒槽座點角(ANB)、上中切牙切緣與鼻根點-上齒槽座點連線的交角(U1/NA)和U1/NA(L1/NB)與A組差異有顯著性意義(P <0.01);B組患者的SNB、L1/NB較A組明顯增大(P<0.05);C組與B組比較,SNB、U1/NA明顯減小,SNA、L1/NB明顯增大(P <0.05)。提示單側完全性脣腭裂患者牙槽嵴植骨治療前、治療後正畸治療效果明顯優于單純治療前或治療後正畸治療,併有利于上頜骨矯正後的穩定性。
배경:부분진악렬환자재9-10세(첨아아근발육1/2-2/3)접수식골후,교치효과불능보지;차7-10세환자식골전후적치료정서목전상불통일。추형속 CT 가재불파배정상조직결구적전제하정학반영조직적미세결구,병통과상배투적계산궤연건획득상관측량수거。목적:이용추형속CT측량결과,비교불동순차적정기연합아조척렬식골치료단측완전성진악렬적료효。방법:선택2012지2013년취진우창주시인민의원적단측완전성진악렬환자60명,분위3조,각20례。A조환자자체가골이식수복아조척렬식골치료후패대보지기보지3개월행정기치료;B조환자정기치료후즉각행자체가골이식수복아조척렬식골치료병후기패대보지기3개월;C조환자정기치료후패대보지기3개월후행자체가골이식수복아조척렬식골치료,식골치료완성후보지기보지3개월。결과여결론:추형속CT결과현시,C조환자접안점-비근점-상치조좌점각(SNA)、접안점-비근점-하치조좌점각(SNB)、상치조좌점-비근점-하치조좌점각(ANB)、상중절아절연여비근점-상치조좌점련선적교각(U1/NA)화U1/NA(L1/NB)여A조차이유현저성의의(P <0.01);B조환자적SNB、L1/NB교A조명현증대(P<0.05);C조여B조비교,SNB、U1/NA명현감소,SNA、L1/NB명현증대(P <0.05)。제시단측완전성진악렬환자아조척식골치료전、치료후정기치료효과명현우우단순치료전혹치료후정기치료,병유리우상합골교정후적은정성。
BACKGROUND:Some cleft lip and palate patients at 9-10 years of age (the canine root development about 1/2-2/3) cannot achieve a good orthodontic outcome after bone grafting, and moreover, there is no unified therapeutic procedure for patients at 7-10 years of age before and after bone grafting. Cone-beam CT can reflect the fine structure accurately under the premise not to destroy normal tissue structure, and have access to the relevant measurement data by matched computer software. OBJECTIVE:To compare the therapeutic effect of orthodontic surgery combined with alveolar cleft bone grafting at different order for treatment of complete unilateral cleft lip and palate. METHODS: Sixty patients with complete unilateral cleft lip and palate admitted at Cangzhou People’s Hospital from 2012 to 2013 were enroled and divided into three groups with 20 in each group: group A, autologous iliac
<br> graft was done folowed by 3 months of wearing orthodontic retainer; Group B, autologous iliac graft was done immediately after orthodontic treatment and then, orthodontic retainer was used for 3 consecutive months; group C, orthodontic retainer was used for 3 consecutive months folowing orthodontic treatment, and then, autologous iliac graft was performed folowed by another 3 consecutive months of wearing orthodontic retainer. RESULTS AND CONCLUSION:There were significant differences between groups A and C in terms of SNA, SNB, ANB, U1-NA and L1-NB (P < 0.01). Group B was significantly higher than the group A in SNB and L1/NB (P < 0.05). Compared with the group B, the SNB and U1/NA were reduced, while the SNA and L1/NB were increased significantly in the group C (P < 0.05). These findings indicate that for complete unilateral cleft lip and palate patients, the orthodontic treatment before and after bone grafting is better than simple pre- or post-grafting orthodontic treatment, which is conductive to the stability of corrected maxila.