CAJ | 학술논문

目的：观察老年糖尿病患者的心血管事件及肿瘤发生风险。方法：选择2004年－2010年在本院内分泌科就诊的糖尿病患者2743例编为糖尿病组，再选择同时期来我院就诊的同年龄段的无糖代谢异常人群2642例作为正常对照组，比较两组患者心血管疾患的发生率和肿瘤标志物的水平（两组患者随访的时间为2～7年）。结果：随访发现，糖尿病组的心血管疾患发生率显著高于正常对照组（21.47％比6.43％，P＜0.05）；肿瘤标志物CA19‐9的水平显著高于正常对照组[（17.89±3.61） kU／L比（9.78±2.64） kU／L ，P＝0.001]，且恶性肿瘤发生率显著高于正常对照组（18.34％比8.18％，P＝0.001）。结论：老年糖尿病患者的心血管事件及肿瘤发生风险显著高于同年龄段的无糖代谢异常人群。
목적：관찰노년당뇨병환자적심혈관사건급종류발생풍험。방법：선택2004년－2010년재본원내분비과취진적당뇨병환자2743례편위당뇨병조，재선택동시기래아원취진적동년령단적무당대사이상인군2642례작위정상대조조，비교량조환자심혈관질환적발생솔화종류표지물적수평（량조환자수방적시간위2～7년）。결과：수방발현，당뇨병조적심혈관질환발생솔현저고우정상대조조（21.47％비6.43％，P＜0.05）；종류표지물CA19‐9적수평현저고우정상대조조[（17.89±3.61） kU／L비（9.78±2.64） kU／L ，P＝0.001]，차악성종류발생솔현저고우정상대조조（18.34％비8.18％，P＝0.001）。결론：노년당뇨병환자적심혈관사건급종류발생풍험현저고우동년령단적무당대사이상인군。
Objective:To observe cardiovascular events and risk of tumor in aged patients with diabetes mellitus (DM) .Methods :A total of 2743 DM patients ,who visited to our department of endocrinology from 2004 to 2010 , were enrolled as DM group ,another 2642 people without glucose metabolic disorder ,who visited to our hospital dur‐ing the same period with the same age ,were regarded as normal control group .Incidence rates of cardiovascular dis‐eases and morbidity of malignant tumor ,levels of tumor markers were compared between two groups (both groups were followed up for 2~7 years) .Results:Follow‐up found that cardiovascular disease rate in DM group was signif‐icantly higher than that of normal control group (21.47% vs .6.43% , P<0.05 );tumor marker CA19‐9 level in DM group was significantly higher than that of normal control group [ (17.89 ± 3.61) kU/L vs .(9.78 ± 2.64) kU/L ,P=0.001] ,and incidence rate of malignant tumor was significantly higher than that of normal control group (18.34% vs .8.18% , P=0.001) .Conclusion:Incidence rate of cardiovascular events and tumor in aged patients with diabetes mellitus is significantly higher than that of people without glucose metabolic disorder of same age .