CAJ | 학술논문

目的：探讨宫颈糜烂与宫颈人乳头状瘤病毒（HPV）亚临床感染（SPI）之间的相关性，为临床诊治提供指导性建议。方法选择2013年1月－2014年1月156例宫颈糜烂患者为观察组，选择同期非宫颈糜烂女性74例为对照组，比较两组患者临床指标，采用SPSS 16．0软件进行统计分析。结果观察组SPI发生率26．92％，明显高于对照组；Ⅲ度宫颈糜烂患者SPI发生率高于Ⅰ、Ⅱ度宫颈糜烂患者，比较差异有统计学意义；SPI患者 HPV阳性率为71．11％，明显高于非SPI患者，比较差异有统计学意义（P＜0．05）。结论宫颈糜烂患者SPI发生率明显较高，同时高危型 HPV高发于SPI患者，因此应该以SPI患者为重点监测对象，预防宫颈癌的发生。
목적：탐토궁경미란여궁경인유두상류병독（HPV）아림상감염（SPI）지간적상관성，위림상진치제공지도성건의。방법선택2013년1월－2014년1월156례궁경미란환자위관찰조，선택동기비궁경미란녀성74례위대조조，비교량조환자림상지표，채용SPSS 16．0연건진행통계분석。결과관찰조SPI발생솔26．92％，명현고우대조조；Ⅲ도궁경미란환자SPI발생솔고우Ⅰ、Ⅱ도궁경미란환자，비교차이유통계학의의；SPI환자 HPV양성솔위71．11％，명현고우비SPI환자，비교차이유통계학의의（P＜0．05）。결론궁경미란환자SPI발생솔명현교고，동시고위형 HPV고발우SPI환자，인차응해이SPI환자위중점감측대상，예방궁경암적발생。
OBJECTIVE To investigate the correlation between cervical erosion and HPV subclinical infections so as to provide guidance and advice for clinical diagnosis and treatment .METHODS Totally 156 cases of patients with cervical erosion from Jan .2013 to Jan .2014 were selected as observation group and 74 non‐cervical erosion pa‐tients in the corresponding period were selected as control group .All data were analyzed by SPSS 16 .0 software . RESULTS The SPI positive rate was 26 .92% in the observation group ,and it was significantly higher than the control group .Patients with cervical erosion reaching the degree Ⅲ had higher SPI positive rate than those with the degree of Ⅰ or Ⅱ .The differences were significant .The HPV positive rate in patients with SPI was 71 .11%which was obviously higher than patients without SPI . The differences were significant ( P < 0 .05 ) . CONCLUSION Patients with cervical erosion are easy to suffer from SPI and meanwhile HPV of the high risk type frequently occurrs in SPI‐positive patients .Therefore we should focus on the SPI‐positive patients to prevent cer‐vical erosion .