中华医院感染学杂志
中華醫院感染學雜誌
중화의원감염학잡지
Chinese Journal of Nosocomiology
2015年
8期
1735-1737
,共3页
丁医峰%袁琼琼%侯一民%干安建
丁醫峰%袁瓊瓊%侯一民%榦安建
정의봉%원경경%후일민%간안건
细菌性肠炎%病原菌%产超广谱β-内酰胺酶%药敏性
細菌性腸炎%病原菌%產超廣譜β-內酰胺酶%藥敏性
세균성장염%병원균%산초엄보β-내선알매%약민성
Bacterial enteritis%Pathogenic bacteria%ESBLs%Drug sensitivity
目的：了解细菌性肠炎的病原菌分布及其药敏性，为该疾病的诊治和控制医院感染提供参考依据。方法选择2011年1月－2013年12月收治的细菌性肠炎患者127例，所有病例均采集粪便标本，鉴定标本中的病原菌种类，并对主要病原菌进行药敏试验，采用SPSS 20．0软件进行统计分析。结果127例细菌性肠炎患者送检的标本中检出183株病原菌，以革兰阴性菌为主，共141株占77．05％；由33株大肠埃希菌中检测出产超广谱β‐内酰胺酶（ESBLs）菌株8株，占24．24％；弗氏志贺菌、大肠埃希菌、沙门菌属对美罗培南、亚胺培南的敏感率均为100．00％；粪肠球菌、金黄色葡萄球菌对利奈唑胺、万古霉素的敏感率均为100．00％。结论通过监测病原菌的分布、变化及其药敏特点，可确立合理的抗菌药物应用方案，有利于细菌性肠炎的治疗。
目的：瞭解細菌性腸炎的病原菌分佈及其藥敏性，為該疾病的診治和控製醫院感染提供參攷依據。方法選擇2011年1月－2013年12月收治的細菌性腸炎患者127例，所有病例均採集糞便標本，鑒定標本中的病原菌種類，併對主要病原菌進行藥敏試驗，採用SPSS 20．0軟件進行統計分析。結果127例細菌性腸炎患者送檢的標本中檢齣183株病原菌，以革蘭陰性菌為主，共141株佔77．05％；由33株大腸埃希菌中檢測齣產超廣譜β‐內酰胺酶（ESBLs）菌株8株，佔24．24％；弗氏誌賀菌、大腸埃希菌、沙門菌屬對美囉培南、亞胺培南的敏感率均為100．00％；糞腸毬菌、金黃色葡萄毬菌對利奈唑胺、萬古黴素的敏感率均為100．00％。結論通過鑑測病原菌的分佈、變化及其藥敏特點，可確立閤理的抗菌藥物應用方案，有利于細菌性腸炎的治療。
목적：료해세균성장염적병원균분포급기약민성，위해질병적진치화공제의원감염제공삼고의거。방법선택2011년1월－2013년12월수치적세균성장염환자127례，소유병례균채집분편표본，감정표본중적병원균충류，병대주요병원균진행약민시험，채용SPSS 20．0연건진행통계분석。결과127례세균성장염환자송검적표본중검출183주병원균，이혁란음성균위주，공141주점77．05％；유33주대장애희균중검측출산초엄보β‐내선알매（ESBLs）균주8주，점24．24％；불씨지하균、대장애희균、사문균속대미라배남、아알배남적민감솔균위100．00％；분장구균、금황색포도구균대리내서알、만고매소적민감솔균위100．00％。결론통과감측병원균적분포、변화급기약민특점，가학립합리적항균약물응용방안，유리우세균성장염적치료。
OBJECTIVE To understand pathogen distribution and drug susceptibility of patients with bacterial enter‐itis so as to provide reference for diagnosis and treatment of the disease and control of hospital infections . METHODS Totally 127 cases of patients with bacterial enteritis from Jan .2011 to Dec .2013 were chosen .Stool specimens of all cases were collected ,types of specimens were identified ,and drug susceptibilities of the main pathogenic bacteria were tested .All data were analyzed by SPSS 20 .0 software .RESULTS Altogether 183 strains of pathogenic bacteria were detected from the specimens of 127 patients with bacterial enteritis .Gram‐negative bacteria dominated the majority with 141 strains ,accounting for 77 .05% .Totally 8 ESBLs‐producing strains were tested from 33 strains of E .coli ,accounting for 24 .24% .Susceptibility rates of major gram‐negative bacteria , Shigella f lexneri ,E .coli and Salmonella ,to meropenem and imipenem were all 100% .Susceptibility rates of major gram‐positive bacteria ,Enterococcus faecalis and Staphylococcus aureus ,to linezolid and vancomycin were both 100% .CONCLUSION By monitoring the distribution changes and drug susceptibility characteristics of patho‐gens ,rational antimicrobial application solutions can be established ,and it is good for the treatment of bacterial enteritis .
