CAJ | 학술논문

目的：观察补肾健脾方对围绝经期及绝经期肥胖妇女体质量及性激素水平的影响，并探讨体质量指数（ BMI）与性激素水平之间的相关性。方法将本院体检的120例围绝经期及绝经期肥胖妇女随机分为2组。治疗组60例采用补肾健脾中药口服治疗，对照组不予治疗。比较2组体质量、BMI、腰围、臀围、腰臀比及血清雌二醇（E2）、卵泡刺激素（FSH）及黄体生成素（LH）水平。结果治疗组用药后，BMI、腰臀比较用药前均下降（P＜0．01，P＜0．05），且与照组同期比较改善明显（P＜0．01）。治疗组用药后E2水平明显升高（P＜0．01），FSH、LH水平均降低（P＜0．01），且与对照组同期比较改善明显（P＜0．01）。结论补肾健脾方能降低围绝经期及绝经期妇女的BMI及腰臀比，能改善其性激素水平。
목적：관찰보신건비방대위절경기급절경기비반부녀체질량급성격소수평적영향，병탐토체질량지수（ BMI）여성격소수평지간적상관성。방법장본원체검적120례위절경기급절경기비반부녀수궤분위2조。치료조60례채용보신건비중약구복치료，대조조불여치료。비교2조체질량、BMI、요위、둔위、요둔비급혈청자이순（E2）、란포자격소（FSH）급황체생성소（LH）수평。결과치료조용약후，BMI、요둔비교용약전균하강（P＜0．01，P＜0．05），차여조조동기비교개선명현（P＜0．01）。치료조용약후E2수평명현승고（P＜0．01），FSH、LH수평균강저（P＜0．01），차여대조조동기비교개선명현（P＜0．01）。결론보신건비방능강저위절경기급절경기부녀적BMI급요둔비，능개선기성격소수평。
Objective To observe the effects of tonifying kidney and spleen herbs on body mass and sex hor-mone levels in perimenopause and menopause women with obesity, and to study the relativity between body mass in-dex ( BMI) and sex hormone levels. Methods 120 perimenopause and menopause women with obesity who had physical examination in our hospital were divided into two groups.60 cases in treatment group were received oral toni-fying kidney and spleen herbs, the control group received no treatment.The body mass, BMI, waist circumference, hip circumference, waist-hip ratio and the level of serum estradiol ( E2 ) , follicle-stimulating hormone ( FSH) and luteinizing hormone ( LH) were compared in two groups.Results After treatment in treatment group, BMI and waist-hip ratio were decreased compared with those in before treatment ( P <0.01, P <0.05), and the improvement was more significant compared with that in control group at the same period ( P <0.01) .The level of E2 after treat-ment in treatment group was significantly increased compared with that in before treatment ( P <0.01), the level of FSH and LH were decreased ( P <0.01), and the improvement was more significant compared with that in control group at the same period ( P <0.01).Conclusion Tonifying kidney and spleen herbs can decrease the BMI and waist-hip ratio in perimenopause and menopause women with obesity, improve the level of sex hormone.