CAJ | 학술논문

目的：探究期待治疗对临床早发型子痫前期患者妊娠结局的影响。方法回顾分析我院2010年5月至2013年2月期间收治的162例早发型子痫前期患者,按发病孕周进行分组(Ⅰ组：<28周,41例；Ⅱ组：28~31周+6,64例；Ⅲ组：32~34周+6,57例),在密切关注母婴情况的条件下实行期待治疗,比较三组患者的期待治疗时长、分娩孕周、并发症及胎儿最终结局等情况。结果三组孕妇的期待治疗时长的排序为Ⅱ组>Ⅲ组>Ⅰ组,组间比较无统计学差异(均P>0.05)；总的并发症发生率排序为Ⅰ组>Ⅲ组>Ⅱ组,Ⅰ组与Ⅱ组、Ⅲ组间比较有统计学差异(均P<0.05)；剖宫产率的组间比较无统计学差异(均P>0.05)；胎儿宫内窘迫、死亡以及新生儿窒息的排序为Ⅰ组>Ⅲ组>Ⅱ组,Ⅰ组与Ⅱ组、Ⅲ组间比较有统计学差异(均P<0.05)；新生儿体重和Apger评分排序为Ⅱ组>Ⅲ组>Ⅰ组,组间比较有统计学差异(均P<0.05)。结论不同发病孕周早发型子痫前期患者期待治疗后妊娠结局的差异较大,发病孕周介于28~31周的患者妊娠结局最好。
목적：탐구기대치료대림상조발형자간전기환자임신결국적영향。방법회고분석아원2010년5월지2013년2월기간수치적162례조발형자간전기환자,안발병잉주진행분조(Ⅰ조：<28주,41례；Ⅱ조：28~31주+6,64례；Ⅲ조：32~34주+6,57례),재밀절관주모영정황적조건하실행기대치료,비교삼조환자적기대치료시장、분면잉주、병발증급태인최종결국등정황。결과삼조잉부적기대치료시장적배서위Ⅱ조>Ⅲ조>Ⅰ조,조간비교무통계학차이(균P>0.05)；총적병발증발생솔배서위Ⅰ조>Ⅲ조>Ⅱ조,Ⅰ조여Ⅱ조、Ⅲ조간비교유통계학차이(균P<0.05)；부궁산솔적조간비교무통계학차이(균P>0.05)；태인궁내군박、사망이급신생인질식적배서위Ⅰ조>Ⅲ조>Ⅱ조,Ⅰ조여Ⅱ조、Ⅲ조간비교유통계학차이(균P<0.05)；신생인체중화Apger평분배서위Ⅱ조>Ⅲ조>Ⅰ조,조간비교유통계학차이(균P<0.05)。결론불동발병잉주조발형자간전기환자기대치료후임신결국적차이교대,발병잉주개우28~31주적환자임신결국최호。
Objective To explore the effect of expectant management on neonatal survival rate for patients with early onset pre-eclampsia. Methods Retrospective analysis 162 cases of pregnant woman with early onset preeclampsia,who were treated with ex-pectant treatment in our hospital from May 2010 to February 2013,according to gestational weeks classification standard,they were di-vided into three groups (Group Ⅰ:<28weeks,41 cases,Group Ⅱ:28 to 31weeks+6,64 cases,Group Ⅲ:32 to 34weeks+6,57 ca-ses),paid close attention to the situation of mother and fetus,treated with expectant management. Gestational weeks,birth time,ex-pectant treatment time,complications and pregnancy outcome of three groups were observed and recorded. Results Expectant treat-ment time of three groups were sequenced:Ⅱ>Ⅲ>Ⅰ,between groups there was no significant difference (P>0. 05);complications rate of three groups were sequenced:Ⅰ>Ⅲ>Ⅱ,GroupⅠhad significant difference with Group Ⅱor Ⅲ (P<0. 05); the difference of cesarean section rate between groups was not significant (P>0. 05);The number of fetal distress,fetal death and asphyxia neonato-rum in three groups were sequenced:Ⅰ>Ⅲ>Ⅱ,GroupⅠhad significant difference with Group Ⅱor Ⅲ (P<0. 05); Birth weight and Apgar scores of three groups were sequenced:Ⅱ>Ⅲ>Ⅰ,between groups there was significant difference (P<0. 05). Conclu-sion About early onset preeclampsia patients, expectant management of differently gestational weeks had distinctly pregnancy out-come,especially for the gestational weeks in 29~31 weeks the outcome of expectant treatment was the best.