CAJ | 학술논문

采用小鼠耳肿胀法对滇白珠种子75%乙醇提取物的石油醚、氯仿、乙酸乙酯、正丁醇萃取物和水溶部分的抗炎效果进行测试。结果表明乙酸乙酯萃取物能显著减轻二甲苯致炎小鼠的耳廓肿胀度。采用色谱技术分离抗炎效果较好的乙酸乙酯萃取物的化学成分,得到8个化合物。通过NMR、IR、MS等波谱法鉴定,8个化合物为：大黄素甲醚(1)、6-乙基-5-羟基-2,7-二甲氧基-1,4-萘醌(2)、杨梅素(3)、对苯二酚(4)、香草酸(5)、β-胡萝卜苷(6)、β-谷甾醇(7)和丁二酸(8)。以上所有化合物都为首次从滇白珠种子中分离得到。
채용소서이종창법대전백주충자75%을순제취물적석유미、록방、을산을지、정정순췌취물화수용부분적항염효과진행측시。결과표명을산을지췌취물능현저감경이갑분치염소서적이곽종창도。채용색보기술분리항염효과교호적을산을지췌취물적화학성분,득도8개화합물。통과NMR、IR、MS등파보법감정,8개화합물위：대황소갑미(1)、6-을기-5-간기-2,7-이갑양기-1,4-내곤(2)、양매소(3)、대분이분(4)、향초산(5)、β-호라복감(6)、β-곡치순(7)화정이산(8)。이상소유화합물도위수차종전백주충자중분리득도。
The extract parts of Gaultheria yunnanensis seeds, which were extracted with petroleum ether, chloroform, ethyl acetate, butanol, and water from 75% ethanol extract, were investigated through pharmacological experiments. The ethyl acetate extract was the antiphlogistic part. Through the use of chromatographic technology, eight compounds were isolated from the antiphlogistic part. Their structures were identified by spectroscopic analyses, such as NMR, IR and MS, etc. . They were physcion (1), 6-ethyl-5-hydroxy-2,7-dimethoxy-1,4-naphthoquinone (2), myricetin (3), 1,4-dihydroxybenzene (4), vanillic acid (5),β-daucosterol (6),β-sitosterol (7) and succinic acid (8). All compounds were isolated from the plant seeds for the first time.