CAJ | 학술논문

目的：探讨多西他赛对局部晚期非小细胞肺癌的生存期、疗效及副反应。方法：40例局部晚期非小细胞肺癌患者随机分组，单放组与联合组，两组病例均采用调强计划，照射剂量60GY，2GY ／次，5次／周，联合组，多西他赛40mg，d1、8、15、22天。结果：联合组和单放组的总有效率分别为80％和50％，有统计学差异（P ＜0．05）。全组中位总生存期15个月，单放组中位总生存期12个月，联合组18个月，两组副反应，患者均能耐受。结论：多西他赛联合三维适行放疗较单纯放疗对局部晚期非小细胞肺癌疗效高，生存期长，并不增加副反应。
목적：탐토다서타새대국부만기비소세포폐암적생존기、료효급부반응。방법：40례국부만기비소세포폐암환자수궤분조，단방조여연합조，량조병례균채용조강계화，조사제량60GY，2GY ／차，5차／주，연합조，다서타새40mg，d1、8、15、22천。결과：연합조화단방조적총유효솔분별위80％화50％，유통계학차이（P ＜0．05）。전조중위총생존기15개월，단방조중위총생존기12개월，연합조18개월，량조부반응，환자균능내수。결론：다서타새연합삼유괄행방료교단순방료대국부만기비소세포폐암료효고，생존기장，병불증가부반응。
To investigate the docetaxel for locally advanced non small cell lung cancer survival,curative effect and side reaction. Methods 40 patients with locally advanced non small cell lung cancer were randomized into test group,and combined group,two cases were with IMRT plan,irradiation dose of 60GY,2GY /,5 times /week,combined with docetaxel group,40mg,D1,8,15,22 days.Results in the combined group and B group total effective rate were 80% and 50%,there were significant differences (P <0.05):a median overall survival of 15 months,only put the median overall survival of 12 months,the joint group of 18 months,two groups of side effects,patients can tolerance.Conclusion docetaxel combined with three dimensional conformal radiotherapy with radiotherapy for locally advanced non small cell lung cancer is high,longer survival time,does not increase the adverse reaction.