CAJ | 학술논문

目的：观察早期持续肠内营养支持对重症脑梗死的临床疗效，探讨其对营养状况的影响。方法：选择102例重症脑梗死患者，随机分为对照组和试验组，每组51例，在常规治疗的基础上，对照组患者早期给予肠外营养支持；试验组患者早期给予肠内营养辅以肠外营养支持，疗程15 d，将两组患者治疗15 d后的营养状态及治疗效果进行对比。结果：治疗前两组患者营养指标比较差异无统计学意义(P>0.05)，经过15 d的治疗后，试验组营养指标显著高于对照组，差异有统计学意义(P<0.05)。试验组肺部感染并发症发生率较对照组低，入住ICU时间及NIHSS评分优于对照组(P<0.05)。结论：早期持续肠内营养支持可更好地促进重症脑梗死患者神经功能的恢复，改善患者的营养状况，影响疾病预后，减少并发症，其机制可能与改善营养状态促进免疫功能的恢复有密切关系。
목적：관찰조기지속장내영양지지대중증뇌경사적림상료효，탐토기대영양상황적영향。방법：선택102례중증뇌경사환자，수궤분위대조조화시험조，매조51례，재상규치료적기출상，대조조환자조기급여장외영양지지；시험조환자조기급여장내영양보이장외영양지지，료정15 d，장량조환자치료15 d후적영양상태급치료효과진행대비。결과：치료전량조환자영양지표비교차이무통계학의의(P>0.05)，경과15 d적치료후，시험조영양지표현저고우대조조，차이유통계학의의(P<0.05)。시험조폐부감염병발증발생솔교대조조저，입주ICU시간급NIHSS평분우우대조조(P<0.05)。결론：조기지속장내영양지지가경호지촉진중증뇌경사환자신경공능적회복，개선환자적영양상황，영향질병예후，감소병발증，기궤제가능여개선영양상태촉진면역공능적회복유밀절관계。
Objective:To observe the efficacy of early enteral nutrition support in severe cerebral infarction patients and its effect on nutritional status.Method:102 cases with severe cerebral infarction were randomly divided into the experimental group and the control group,51 cases in each group.They both were given fundamental treatment.The experimental group was given extra enteral nutrition supportive,the control group was given parenteral nutrition.The nutritional status and treatment effect in two groups were compared.Result:Before treatment,there were no marked differences between the two groups in ALB,HB,PA(P>0.05).After 15 days of treatment,the above indicators of the experimental group were all higher than those of the control group,with statistical significance(P<0.05),the incidence of the lung infections in the experimental group was less than the control group,the time of ICU and score of HINSS in the experimental group were better than those in the control group(P<0.05).Conclusion:Early enteral nutrition support can promote the recovery of neurological function in patients with severe cerebral infarction and improve the prognosis of the disease and reduce the lung infections,promote the recovery of immune function.