CAJ | 학술논문

目的：探讨脑钠肽对鉴别诊断肾性与肾前性急性肾损伤的价值。方法：按标准纳入86例急性肾损伤患者，根据病理分为肾前性AKI组(42例)和肾性AKI组(44例)，收集患者的一般资料并记录、比较两组患者血清Scr、BUN/Scr、血红蛋白、脑钠肽(BNP)；尿钠量和尿渗透压等指标。结果：两组患者血清Scr、BUN/Scr、血红蛋白、脑钠肽(BNP)；尿钠量和尿渗透压比较差异均有统计学意义(P<0.05)，经受试者工作特征曲线(ROC曲线)分析显示BNP更具有鉴别诊断价值。结论：BNP在鉴别诊断肾前性与肾性AKI方面具有无创与准确的优点，具有鉴别两者的价值。
목적：탐토뇌납태대감별진단신성여신전성급성신손상적개치。방법：안표준납입86례급성신손상환자，근거병리분위신전성AKI조(42례)화신성AKI조(44례)，수집환자적일반자료병기록、비교량조환자혈청Scr、BUN/Scr、혈홍단백、뇌납태(BNP)；뇨납량화뇨삼투압등지표。결과：량조환자혈청Scr、BUN/Scr、혈홍단백、뇌납태(BNP)；뇨납량화뇨삼투압비교차이균유통계학의의(P<0.05)，경수시자공작특정곡선(ROC곡선)분석현시BNP경구유감별진단개치。결론：BNP재감별진단신전성여신성AKI방면구유무창여준학적우점，구유감별량자적개치。
Objective:To explore the value of brain natriuretic peptide(BNP) on differential diagnosis between prerenal acute renal injury and renal acute kidney injury.Method:According to the standard,86 cases with acute kidney injury were brought into this study and they were divided into prerenal AKI group(42 cases) and renal AKI group(44 cases) on the basic of pathology,the general data was collected,the serum creatinine(Scr), blood urea nitrogen(BUN)/Scr,hemoglobin,BNP,urinary sodium content and urine osmotic pressure were recorded and compared.Result:There were obvious differences between two groups of patients on serum creatinine(Scr),blood urea nitrogen(BUN)/Scr,hemoglobin,BNP,urinary sodium content and urine osmotic pressure(P<0.05);receiver operator characteristic curve(ROC curve) analysis showed that BNP had more value in differential diagnosis. Conclusion:BNP has differential diagnosis value of prerenal acute renal injury and renal acute kidney injury with advantages of no pain and accurate.