CAJ | 학술논문

目的探讨精神分裂症患者元认知能力与共情能力及精神症状的关系.方法采用修订版元认知评估量表(MAS-A)和中文版人际反应指针量表(IRI-C)对77例处于疾病治疗稳定期的精神分裂症患者和34例神经症性障碍患者进行元认知和共情能力评估,86例正常者作IRI-C评估,精神分裂症患者作阳性和阴性症状量表(PANSS)评估.结果精神分裂症患者MAS-A总分[(8.8±3.3)分]及其自我反省[(3.4±1.1)分]、理解他人[(2.5±1.0)分]、去中心化[(0.4±0.6)分]和控制分量表分[(2.4±1.1)分]均低于神经症性障碍患者[分别为:(12.7±3.4)分、(4.9±1.2)分、(3.3±0.9)分、(1.1±0.7)分、(3.3±1.2)分],差异具有统计学意义(均P＜0.01).相关分析显示,精神分裂症患者元认知评分与共情评分之间呈正相关(r=0.229～0.305,P＜0.05),与PANSS评分间呈负相关(r=-0.248～-0.491,P＜0.05),控制症状评分后,元认知评分与共情评分间的相关性仍然存在.结论精神分裂症患者元认知能力受损,元认知损害与共情缺陷间存在关联,提示两者间可能存在共同的病理生理基础.
목적 탐토정신분렬증환자원인지능력여공정능력급정신증상적관계.방법 채용수정판원인지평고량표(MAS-A)화중문판인제반응지침량표(IRI-C)대77례처우질병치료은정기적정신분렬증환자화34례신경증성장애환자진행원인지화공정능력평고,86례정상자작IRI-C평고,정신분렬증환자작양성화음성증상량표(PANSS)평고.결과 정신분렬증환자MAS-A총분[(8.8±3.3)분]급기자아반성[(3.4±1.1)분]、리해타인[(2.5±1.0)분]、거중심화[(0.4±0.6)분]화공제분량표분[(2.4±1.1)분]균저우신경증성장애환자[분별위:(12.7±3.4)분、(4.9±1.2)분、(3.3±0.9)분、(1.1±0.7)분、(3.3±1.2)분],차이구유통계학의의(균P＜0.01).상관분석현시,정신분렬증환자원인지평분여공정평분지간정정상관(r=0.229～0.305,P＜0.05),여PANSS평분간정부상관(r=-0.248～-0.491,P＜0.05),공제증상평분후,원인지평분여공정평분간적상관성잉연존재.결론 정신분렬증환자원인지능력수손,원인지손해여공정결함간존재관련,제시량자간가능존재공동적병리생리기출.
Objective To explore the relationship among the metacognitive ability,empathy and psychotic symptoms in schizophrenic patients.Methods Seventy-seven schizophrenic patients in a post-acute phase of illness and thirty-four patients with neuroses were assessed with the abbreviated-metacognition assessment scale (MAS-A) and the interpersonal reactivity index-C(IRI-C),and eighty-six normal subjects were rated with the IRIC.Additionally,psychotic symptoms of the schizophrenic patients were assessed with the positive and negative syndrome scale(PANSS).Results The MAS-A total score,the subscores in self-reflectivity,understanding of other' mind,decentration,mastery of MAS-A (respectively (8.8±3.3),(3.4± 1.1),(2.5± 1.0),(0.4±0.6),(2.4± 1.1)) were significantly lower in the schizophrenic patients group than those in the neurosis patients group (respectively (12.7±3.4),(4.9± 1.2),(3.3±0.9),(1.1±0.7),(3.3± 1.2)) (all P＜0.01).Correlation analysis showed that the MAS-A scores were significantly negatively correlated with the PANSS scores (r=-0.248--0.491,P＜0.05),and the MAS-A scores had significantly positively correlation with the IRI-C scores (r=0.229-0.305,P＜0.05),the relationship were persisted when the scores of PANSS were statistically controlled.Conclusion The metacognitive ability of schizophrenic patients are impaired,and the correlation between impaired matacognition and empathy deficit suggests that they share the same physiopathologic basis.