CAJ | 학술논문

目的：建立参芎葡萄糖注射液中总糖含量的良好测定方法。方法：采用紫外分光光度法和蒽酮－硫取法，以葡萄糖为对照品，对参芎葡萄糖注射液中总糖进行含量测定。结果：建立了以葡萄糖为对照品，紫外分光光度法测定参芎葡萄糖注射液中总糖的含量测定方法，且浓度在0．008～0．03 g／L 范围内与吸光度线性关系良好，A ＝35．50C －0．04180，r ＝0．9993，平均回收率为103．1％，RSD 为2．9％。结论：蒽酮－硫酸法测定参芎葡萄糖注射液中总糖含量，测定方法简便、准确可靠，可用于该制剂的质量控制。
목적：건립삼궁포도당주사액중총당함량적량호측정방법。방법：채용자외분광광도법화은동－류취법，이포도당위대조품，대삼궁포도당주사액중총당진행함량측정。결과：건립료이포도당위대조품，자외분광광도법측정삼궁포도당주사액중총당적함량측정방법，차농도재0．008～0．03 g／L 범위내여흡광도선성관계량호，A ＝35．50C －0．04180，r ＝0．9993，평균회수솔위103．1％，RSD 위2．9％。결론：은동－류산법측정삼궁포도당주사액중총당함량，측정방법간편、준학가고，가용우해제제적질량공제。
Objective:To establish the method for the determination of total sugar in Shenxiong glu-cose injection.Methods:Adopting UV spectrophotometry and anthrone sulfur method,using glucose as reference to measure total sugar content of Shenxiong injection.Results:Established the method of using glucose as reference to test total sugar of Shenxiong glucose injection by UV spectrophotometry, and it showed a good linear relationship between the absorbance and the concentration between 0.008~0.03 g/L,A =35.50C ~0.0418 0,r =0.999 3;the average recovery was 103.1%,RSD was 2.9%.Conclusions:The method is practical,accurate and reliable,can be used as quality control method of Shenxiong glucose injection.