胃肠病学和肝病学杂志
胃腸病學和肝病學雜誌
위장병학화간병학잡지
CHINESE JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
2015年
4期
441-443
,共3页
饮酒量%酒精性脂肪肝%非酒精性脂肪肝%代谢综合征
飲酒量%酒精性脂肪肝%非酒精性脂肪肝%代謝綜閤徵
음주량%주정성지방간%비주정성지방간%대사종합정
Alcohol consumption%Alcoholic fatty liver disease%Nonalcoholic fatty liver disease%Metabolic syn-drome
目的：探讨脂肪肝患者饮酒及饮酒量多少对代谢综合征（metabolic syndrome，MS）发生的影响。方法回顾性分析中国医科大学体检中心诊断为脂肪肝的1868例患者，按照脂肪肝的诊断标准将其分为酒精性脂肪肝（ alcoholic fatty liver disease ， AFLD）和非酒精性脂肪肝（nonalcoholic fatty liver disease，NAFLD），后者分为绝对不饮酒的脂肪肝（N-NAFLD）和饮酒量没有达到AFLD诊断标准的脂肪肝（D-NAFLD），分析比较其患MS的风险。结果与NAFLD 相比，AFLD患者的收缩压（SBP）、舒张压（DBP）、甘油三酯（TG）、高密度脂蛋白（HDLC）、空腹血糖（GLU）显著增高（P＜0．05），而体质量指数（BMI）在两组间比较，差异无统计学意义（P＞0．05）；与N-NAFLD相比，D-NAFLD患者SBP、HDLC、GLU显著降低（P＜0．05），而BMI、TG显著升高（P＜0．05）， DBP在两组间比较，差异无统计学意义（P＞0．05）。结论 AFLD发生MS的风险明显高于NAFLD。与N-NAFLD相比，D-NAFLD患高血压、糖尿病的风险降低，而血脂异常症及肥胖症的发病风险升高。
目的：探討脂肪肝患者飲酒及飲酒量多少對代謝綜閤徵（metabolic syndrome，MS）髮生的影響。方法迴顧性分析中國醫科大學體檢中心診斷為脂肪肝的1868例患者，按照脂肪肝的診斷標準將其分為酒精性脂肪肝（ alcoholic fatty liver disease ， AFLD）和非酒精性脂肪肝（nonalcoholic fatty liver disease，NAFLD），後者分為絕對不飲酒的脂肪肝（N-NAFLD）和飲酒量沒有達到AFLD診斷標準的脂肪肝（D-NAFLD），分析比較其患MS的風險。結果與NAFLD 相比，AFLD患者的收縮壓（SBP）、舒張壓（DBP）、甘油三酯（TG）、高密度脂蛋白（HDLC）、空腹血糖（GLU）顯著增高（P＜0．05），而體質量指數（BMI）在兩組間比較，差異無統計學意義（P＞0．05）；與N-NAFLD相比，D-NAFLD患者SBP、HDLC、GLU顯著降低（P＜0．05），而BMI、TG顯著升高（P＜0．05）， DBP在兩組間比較，差異無統計學意義（P＞0．05）。結論 AFLD髮生MS的風險明顯高于NAFLD。與N-NAFLD相比，D-NAFLD患高血壓、糖尿病的風險降低，而血脂異常癥及肥胖癥的髮病風險升高。
목적：탐토지방간환자음주급음주량다소대대사종합정（metabolic syndrome，MS）발생적영향。방법회고성분석중국의과대학체검중심진단위지방간적1868례환자，안조지방간적진단표준장기분위주정성지방간（ alcoholic fatty liver disease ， AFLD）화비주정성지방간（nonalcoholic fatty liver disease，NAFLD），후자분위절대불음주적지방간（N-NAFLD）화음주량몰유체도AFLD진단표준적지방간（D-NAFLD），분석비교기환MS적풍험。결과여NAFLD 상비，AFLD환자적수축압（SBP）、서장압（DBP）、감유삼지（TG）、고밀도지단백（HDLC）、공복혈당（GLU）현저증고（P＜0．05），이체질량지수（BMI）재량조간비교，차이무통계학의의（P＞0．05）；여N-NAFLD상비，D-NAFLD환자SBP、HDLC、GLU현저강저（P＜0．05），이BMI、TG현저승고（P＜0．05）， DBP재량조간비교，차이무통계학의의（P＞0．05）。결론 AFLD발생MS적풍험명현고우NAFLD。여N-NAFLD상비，D-NAFLD환고혈압、당뇨병적풍험강저，이혈지이상증급비반증적발병풍험승고。
Objective To determine the effects of alcohol consumption on the prevalence of metabolic syndrome (MS) in patients with fatty liver disease (FLD).Methods A total of 1 868 patients diagnosed as FLD in Health Check Center of China Medical University were selected .FLD patients were divided into alcoholic fatty liver disease ( AFLD) group and nonalcoholic fatty liver disease ( NAFLD) group in accordance with the diagnostic criteria of FLD . The latter was further divided into N-NAFLD group ( those who never drank ) and D-NAFLD group ( those who drank but did not meet the diagnostic criteria for AFLD ).Results The levels of SBP, DBP, TG, HDLC and GLU in AFLD group were higher than those in NAFLD group ( P<0 .05 ) , while BMI showed no significant difference between two groups (P>0.05).The levels of SBP, HDLC, GLU in D-NAFLD group were lower than those in N-NAFLD group (P<0.05), while the levels of BMI and TG were higher (P<0.05), but there was no significant difference of DBP level between two groups ( P>0 .05 ) .Conclusion The risk of MS in AFLD is significantly higher than that in NAFLD .The risks of hypertension and diabetes in D-NAFLD group are relatively lower , while the risks of dyslipidemia and obesity are higher compared with N-NAFLD group.
