CAJ | 학술논문

目的：探讨扩散加权成像(DWI)对强直性脊柱炎(AS)活动性骶髂关节炎的诊断价值。方法63例 AS 患者均行骶髂关节斜冠状位 DWI 及 STIR 序列扫描,测量表观扩散系数(ADC)值及进行加拿大脊柱骨关节研究协会评分系统(SPARCC)评分,分析其与临床 Bath 强直性脊柱炎疾病活动指数(BASDAI)评分的关系。将患者按病情分为活动组、稳定组,并与健康志愿者骶髂关节 ADC 值进行比较。结果患者的 SPARCC 评分与 ADC 值(r=0.781,P <0.001)、BASDAI 评分与 ADC 值(r=0.854, P <0.001)以及 SPARCC 评分与 BASDAI 评分(r=0.805,P <0.001)均呈正相关。活动组骶髂关节的 ADC 值中位数(0.704×10-3 mm2/s)高于稳定组(0.543×10-3 mm2/s)及对照组(0.431×10-3 mm2/s),3组间 ADC 值差异均有统计学意义。结论SPARCC 评分及 DWI 均可以作为 MRI 评价骶髂关节炎活动性的重要指标。DWI 序列成像速度快,通过测量病变区 ADC 值可以量化分析,是骶髂关节成像的理想选择。
목적：탐토확산가권성상(DWI)대강직성척주염(AS)활동성저가관절염적진단개치。방법63례 AS 환자균행저가관절사관상위 DWI 급 STIR 서렬소묘,측량표관확산계수(ADC)치급진행가나대척주골관절연구협회평분계통(SPARCC)평분,분석기여림상 Bath 강직성척주염질병활동지수(BASDAI)평분적관계。장환자안병정분위활동조、은정조,병여건강지원자저가관절 ADC 치진행비교。결과환자적 SPARCC 평분여 ADC 치(r=0.781,P <0.001)、BASDAI 평분여 ADC 치(r=0.854, P <0.001)이급 SPARCC 평분여 BASDAI 평분(r=0.805,P <0.001)균정정상관。활동조저가관절적 ADC 치중위수(0.704×10-3 mm2/s)고우은정조(0.543×10-3 mm2/s)급대조조(0.431×10-3 mm2/s),3조간 ADC 치차이균유통계학의의。결론SPARCC 평분급 DWI 균가이작위 MRI 평개저가관절염활동성적중요지표。DWI 서렬성상속도쾌,통과측량병변구 ADC 치가이양화분석,시저가관절성상적이상선택。
Objective To evaluate the value of diffusion weighted imaging (DWI)in diagnosing active sacroiliitis of ankylosing spondylitis(AS)Methods 63 cases with AS confirmed clinically were included.The patients were evaluated by Bath ankylosing spondylitis disease activity index (BASDAI)score and examined by MRI with oblique coronal DWI and STIR sequence in the sacroili-ac joint.The ADC value and Spondyloarthritis Research Consortium of Canada (SPARCC)score were measured in all patients.Cor-relative analysis was performed among BASDAI score,SPARCC score and ADC value.Patients were divided into activity and stability group according to the condition,which were compared with the ADC features of the sacroiliac joint in healthy volunteers.Results The Spearman correlation analysis showed that in patients SPARCC score and ADC values (r =0.781,P <0.001 ),BASDAI score and ADC values (r=0.854,P <0.001),SPARCC score and BASDAI score (r =0.805,P <0.001)were positively correlated.The median ADC values in the sacroiliac joint of activity group (0.704×10 -3 mm2/s)was higher than that in the stable group(0.543× 10 -3 mm2/ s )and the control group (0.431×10 -3 mm2/ s).The ADC values between the activity、stability and control group were statistically significant differences.Conclusion SPARCC score and DWI are important indexes for MRI evaluation of sacroiliac ar-thritis activity.DWI is a fast imaging sequence,can be quantified by measuring the ADC value of the lesion area,and is the ideal choice for sacroiliac joint imaging.