CAJ | 학술논문

目的：观察浓替硝唑含漱液局部应用治疗冠周炎的临床疗效。方法：将80例冠周炎患者随机分成观察组和对照组，每组40例，观察组采用浓替硝唑含漱液局部治疗，对照组采用传统的双氧水、生理盐水局部治疗；观察治疗后第3天两组冠周炎患者的临床疗效及对4类口腔厌氧菌的杀菌效果及清除率。结果：治疗后，观察组和对照组患者的总有效率分别为100％和65％，观察组的有效率明显高于对照组，差异有统计学意义（P ＜0．05）；两组患者治疗后，对4类口腔主要厌氧菌均有一定的杀菌效果，总清除率分别为72％和49％，差异有统计学意义（P ＜0．05）。结论：浓替硝唑含漱液局部治疗冠周炎疗效显著，值得临床推广应用。
목적：관찰농체초서함수액국부응용치료관주염적림상료효。방법：장80례관주염환자수궤분성관찰조화대조조，매조40례，관찰조채용농체초서함수액국부치료，대조조채용전통적쌍양수、생리염수국부치료；관찰치료후제3천량조관주염환자적림상료효급대4류구강염양균적살균효과급청제솔。결과：치료후，관찰조화대조조환자적총유효솔분별위100％화65％，관찰조적유효솔명현고우대조조，차이유통계학의의（P ＜0．05）；량조환자치료후，대4류구강주요염양균균유일정적살균효과，총청제솔분별위72％화49％，차이유통계학의의（P ＜0．05）。결론：농체초서함수액국부치료관주염료효현저，치득림상추엄응용。
Objective:To observe the clinical efficacy of concentrated tinidazole gargles on pericoro-nitis.Methods:Eighty cases with pericoronitis were randomly divided into experimental group treated with concentrated tinidazole gargles and control group treated with conventional hydrogen peroxide and saline.Clinical efficacy of both the two groups in the 3 rd day after treatment was observed,bactericidal effect and clearance rate of the four kinds of oral anaerobes were detected.Results:The clinical effi-cacy of the experimental group and the control group was 100% and 65% respectively,and the differ-ence was significant (P <0.05).Bactericidal effect on the four kinds of oral anaerobes in experimen-tal group was better than that in control group.Further,the total clearance rate of the oral anaerobes was 72% in the experimental group and 49% in the control group,the difference was statistically sig-nificant as well (P <0.05).Conclusions:The concentrated tinidazole gargles in treatment of perico-ronitis is superior to conventional method ,and this treatment is worthy of clinical application.