CAJ | 학술논문

目的：探讨影响胃上皮内瘤变的危险因素及应用内镜对检测胃上皮内瘤变准确性的影响因素。方法选取因胃黏膜病变行内镜下切除术治疗的患者102例，其中73例证实为胃上皮内瘤变作为瘤变组，随机选择健康体检者70名作为对照组，观察影响胃上皮内瘤变的危险因素及应用内镜对检测胃上皮瘤变准确性的影响因素。结果长期饮酒、不吃早餐、喜好油腻食物、熬夜及伴幽门螺旋杆菌（ Helicobacter pylori ， H．pylori）感染是引起胃上皮内瘤变的危险因素；病变大小是影响内镜活检病理诊断准确性的独立相关因素。结论积极干预胃萎缩性胃炎或肠化生病变的患者长期饮酒、不吃早餐、喜好油腻食物、熬夜及伴H．pylori感染等危险因素；对于直径≥3 cm的病变，应当直接行内镜下切除术。
목적：탐토영향위상피내류변적위험인소급응용내경대검측위상피내류변준학성적영향인소。방법선취인위점막병변행내경하절제술치료적환자102례，기중73예증실위위상피내류변작위류변조，수궤선택건강체검자70명작위대조조，관찰영향위상피내류변적위험인소급응용내경대검측위상피류변준학성적영향인소。결과장기음주、불흘조찬、희호유니식물、오야급반유문라선간균（ Helicobacter pylori ， H．pylori）감염시인기위상피내류변적위험인소；병변대소시영향내경활검병리진단준학성적독립상관인소。결론적겁간예위위축성위염혹장화생병변적환자장기음주、불흘조찬、희호유니식물、오야급반H．pylori감염등위험인소；대우직경≥3 cm적병변，응당직접행내경하절제술。
Objective To explore the dangerous factors affecting gastric intraepithelial neoplasia and the influence factors for accuracy of endoscopy that be applied to detect gastric intraepithelial neoplasia .Methods There were 102 patients selected for gastric mucosal lesions under endoscopic resection treatment , and 73 of them confirmed for intraepi-thelial neoplasia were selected as the neoplasia group , while 70 healthy persons were collected as healthy controls .The dangerous factors affecting gastric intraepithelial neoplasia and the influence factors for accuracy of endoscopy be applied to detect gastric intraepithelial neoplasia were explored .Results The dangerous factors that causing stomach intraepithe-lial neoplasia were long-term drinking, skipping breakfast , greasy food, staying up late and Helicobacter pylori (H.py-lori) infection.The lesion size was independent related factors influencing the accuracy of the endoscopic biopsy patho -logic diagnosis.Conclusion The patients with long-term drinking, skipping breakfast , greasy food, staying up late or H.pylori infection that suffered from stomach atrophic gastritis or intestinal metaplasia should be active intervented .And lesions of a diameter of 3 cm or more should be treated with endoscopic submucosal resection .