CAJ | 학술논문

[目的]观察胃底折叠术治疗胃食管反流病对高血压的影响。[方法]回顾性分析2011‐06—2012‐08期间20例行腹腔镜胃底折叠术的胃食管反流病合并高血压患者的临床资料，依照反流病诊断问卷在手术前和手术后进行反流症状评分。[结果]20例均成功实施腹腔镜手术并于术后第12个月随访。反流总积分（Sc）由术前20.0±9.5降至术后0.5±0.9（P＜0.05），术后收缩压下降了（11.0±12.0）mm Hg（1 mmHg＝0.133 kPa），舒张压下降了（9.0±11.5）m m H g （均 P＜0.05）。术后随访12个月11例血压恢复正常，停药时间均在9个月以上；2例减少2种降压药，1例减少1种降压药；6例无效，仍用术前降压药物。[结论]胃食管反流病与部分高血压密切相关，腹腔镜胃底折叠术治疗胃食管反流病合并高血压安全、有效。
[목적]관찰위저절첩술치료위식관반류병대고혈압적영향。[방법]회고성분석2011‐06—2012‐08기간20례행복강경위저절첩술적위식관반류병합병고혈압환자적림상자료，의조반류병진단문권재수술전화수술후진행반류증상평분。[결과]20례균성공실시복강경수술병우술후제12개월수방。반류총적분（Sc）유술전20.0±9.5강지술후0.5±0.9（P＜0.05），술후수축압하강료（11.0±12.0）mm Hg（1 mmHg＝0.133 kPa），서장압하강료（9.0±11.5）m m H g （균 P＜0.05）。술후수방12개월11례혈압회복정상，정약시간균재9개월이상；2례감소2충강압약，1례감소1충강압약；6례무효，잉용술전강압약물。[결론]위식관반류병여부분고혈압밀절상관，복강경위저절첩술치료위식관반류병합병고혈압안전、유효。
Objective]To observe the association between gastroesophageal reflux disease (GERD)and hypertension .To evaluate the efficiency of laparoscopic Nissen fundoplication in the treatment of hyperten‐sion induced by GERD.[Methods]We retrospectively analyzed the clinical data of 20 patients with hyper‐tension who underwent laparoscopic fundoplication for GERD during the period of June 2011 and August 2012.[Results]All the patients were successfully treated with laparoscopic surgery and followed for 12 months.The total reflux score(Sc)calculated from the questionnaire decreased from 20.0 ± 9.5(preopera‐tive score)to 0.5 ± 0.9(postoperative score) ,which indicated that the GERD was treated successfully (P<0.05).One year after the operation ,the systolic blood pressure decreased by (11.0 ± 12.0)mmHg (P<0.05)and the diastolic blood pressure(DBP)decreased by(9.0 ± 11.5)mmHg(P<0.05).Furthermore ,the hypertension medication was discontinued in 11 patients ,the dose was decreased in 3 patients ,and the med‐ication was continued in 6 patients.[Conclusion]GERD is closely related with hypertension .The laparo‐scopic Nissen fundoplication is a safe and effective treatment in patients with the hypertension induced by GERD.