CAJ | 학술논문

目的：检测患牙周炎孕妇牙周基础治疗前后血清C反应蛋白（ CRP）浓度的变化，为预防早产和低体重儿的发生提供科学依据。方法根据孕妇牙周状况分为牙周健康组和牙周炎组。牙周健康孕妇仅进行口腔卫生宣教，患牙周炎孕妇在知情同意下接受牙周基础治疗。记录初诊和每次复诊牙周探诊深度和临床附着丧失，同时检测血清CRP浓度。结果牙周健康孕妇牙周组织始终处于良好状态，CRP浓度亦维持在（1．17±1．03）mg／L左右；患牙周炎孕妇经过牙周基础治疗探诊深度和临床附着丧失都明显改善，CRP水平也由（4．16±1．45） mg／L降低到（1．90±1．13）mg／L，差异具有显著性意义（P＜0．05）。结论牙周基础治疗改善患牙周炎孕妇牙周组织炎症的同时显著降低其血清CRP浓度。
목적：검측환아주염잉부아주기출치료전후혈청C반응단백（ CRP）농도적변화，위예방조산화저체중인적발생제공과학의거。방법근거잉부아주상황분위아주건강조화아주염조。아주건강잉부부진행구강위생선교，환아주염잉부재지정동의하접수아주기출치료。기록초진화매차복진아주탐진심도화림상부착상실，동시검측혈청CRP농도。결과아주건강잉부아주조직시종처우량호상태，CRP농도역유지재（1．17±1．03）mg／L좌우；환아주염잉부경과아주기출치료탐진심도화림상부착상실도명현개선，CRP수평야유（4．16±1．45） mg／L강저도（1．90±1．13）mg／L，차이구유현저성의의（P＜0．05）。결론아주기출치료개선환아주염잉부아주조직염증적동시현저강저기혈청CRP농도。
Objective To investigate serum C-reactive protein level after periodontal nonsurgical therapy in pregnant women with periodontitis and to provide scientific evidence in preventing the incidence of premature and low birth weight in-fants.Methods Pregnant women were divided into periodontal health group and periodontitis group according to the perio-dontal status.All patients were organized to study and learn oral health.Periodontal nonsurgical therapy was performed in periodontitis group with informed consent.Probing depth,clinical attachment loss and serum C-reactive protein level of each pregnant woman were measured in each visit.Results Periodontal tissue was in good status and serum C-reactive protein concentration remained about at (1.17 ±1.03) mg/L in periodontal healthy women throughout the study period.Af-ter periodontal nonsurgical treatment,probing depth and clinical attachment loss in pregnant women with periodontitis were significantly improved,and serum C-reactive protein concentration decreased from (4.16 ±1.45)mg/L to (1.90 ±1.13) mg/L (P<0.05).Conclusions Periodontal inflammation was improved and serum C-reactive protein concentration was reduced significantly in pregnant women with periodontitis by periodontal nonsurgical therapy,which would be beneficial to decrease premature birth and low birth weight infants.