CAJ | 학술논문

目的：分析鼻塞式同步间歇指令通气（ nSIMV）在早产儿原发性呼吸暂停（ AOP）中的临床应用效果。方法应用nSIMV模式治疗AOP早产儿共22例，与既往应用鼻塞式持续气道正压通气（ nCPAP）模式治疗的AOP早产儿共22例进行分析，比较两组患儿治疗前后临床症状、血气指标、治疗效果及预后的变化。结果经nSIMV模式治疗的婴儿每小时呼吸暂停发生频率以及心率下降频率比经nCPAP模式治疗的早产儿明显降低，差异有显著性意义（P＜0．05），nSIMV组需气管插管行呼吸机通气的比率（9．1％）、CO2潴留比率（4．5％）和胃肠道并发症比率（4．5％）明显低于nCPAP组（27．3％、18．2％和13．6％），差异有显著性意义（P＜0．05）。结论 nSIMV能更有效地对AOP早产儿进行呼吸支持治疗。
목적：분석비새식동보간헐지령통기（ nSIMV）재조산인원발성호흡잠정（ AOP）중적림상응용효과。방법응용nSIMV모식치료AOP조산인공22례，여기왕응용비새식지속기도정압통기（ nCPAP）모식치료적AOP조산인공22례진행분석，비교량조환인치료전후림상증상、혈기지표、치료효과급예후적변화。결과경nSIMV모식치료적영인매소시호흡잠정발생빈솔이급심솔하강빈솔비경nCPAP모식치료적조산인명현강저，차이유현저성의의（P＜0．05），nSIMV조수기관삽관행호흡궤통기적비솔（9．1％）、CO2저류비솔（4．5％）화위장도병발증비솔（4．5％）명현저우nCPAP조（27．3％、18．2％화13．6％），차이유현저성의의（P＜0．05）。결론 nSIMV능경유효지대AOP조산인진행호흡지지치료。
Objective To evaluate the efficacy of nasal synchronized intermittent mandatory ventilation ( nSIMV) in pre-term infants with primary apnea of premature ( AOP) .Methods We collected 22 cases of preterm infants with AOP who were treated with nSIMV,and compared with 22 cases who were previously treaded with nasal continuous positive airway pressure ( nCPAP) .Clinical symptoms,signs and blood gas results following nSIMV or nCPAP in the two groups were com-pared.Results The infants receiving nSIMV had a greater reduction of apneic spells and a greater decrease in bradycardia than those receiving nCPAP.Compared to the nCPAP group,the nSIMV group had a lower incidence of respiratory failure (9.1%vs.27.3%;P<0.05),a lower incidence of hypercarbonia (4.5%vs.18.2%;P<0.05) and a lower incidence of gastrointestinal complications (4.5%vs.13.6%;P<0.05).Conclusion nSIMV is more effective in respiratory sup-port in preterm infants with AOP.