CAJ | 학술논문

目的：探讨匹多莫德辅助治疗儿童毛细支气管炎的临床疗效。方法收集2009年2月－2010年4月儿科门诊及病房符合毛细支气管炎诊断的患儿50例，随机分为治疗组与对照组各25例。对照组采用布地奈德，沙丁胺醇交替雾化，采用抗病毒药物，根据感染情况添加抗生素，并给予激素静脉滴注。治疗组在对照组基础上加用匹多莫德片。比较2组患儿治疗后的临床疗效。结果对照组总有效率为72．0％，治疗组总有效率为84．0％，治疗组患儿治疗后疗程较对照组缩短，差异有统计学意义（ P＜0．05）。治疗期间未见明显不良反应，患儿依从性100．0％。结论匹多莫德用于儿童反复呼吸道感染临床急性期治疗、缓解期预防均有明显疗效，且无明显不良反应，为口服剂型，使用方便，减轻了患儿的痛苦，并减少了在院时间，值得推广。
목적：탐토필다막덕보조치료인동모세지기관염적림상료효。방법수집2009년2월－2010년4월인과문진급병방부합모세지기관염진단적환인50례，수궤분위치료조여대조조각25례。대조조채용포지내덕，사정알순교체무화，채용항병독약물，근거감염정황첨가항생소，병급여격소정맥적주。치료조재대조조기출상가용필다막덕편。비교2조환인치료후적림상료효。결과대조조총유효솔위72．0％，치료조총유효솔위84．0％，치료조환인치료후료정교대조조축단，차이유통계학의의（ P＜0．05）。치료기간미견명현불량반응，환인의종성100．0％。결론필다막덕용우인동반복호흡도감염림상급성기치료、완해기예방균유명현료효，차무명현불량반응，위구복제형，사용방편，감경료환인적통고，병감소료재원시간，치득추엄。
Objective To study the clinical effect of pidotimod in the adjuvant treatment of capillary bronchitis in children.Methods 50 cases of children with capillary bronchitis were randomly divided into treatment group and control group,each of 25 cases.The control group received budesonide and salbutamol alternative atomization ,antiviral therapy,antibi-otics treatment according to the infection degree and hormone infusion .Based on the control group , the treatment group was added with pidotimod for treatment .The clinical efficacy of 2 groups was compared .Results The total effective rate of treat-ment group was 84.0%,while the control group was 72.0%,and the course of treatment in the treatment significantly short-ened compared with the control group,the differences were statistically significant (P<0.05).During the treatment period, there was no obvious adverse reaction .The compliance of children was 100%.Conclusion The curative effect of pidotimod is obvious in the clinical treatment of acute period of children with recurrent respiratory tract infection and the prevention of re -mission stage,with no obvious adverse reaction ,for oral dosage,convenient to use,which reduces the pain of the patients and Reduces the length of stay .It is worthy of popularization .