CAJ | 학술논문

目的：探讨噻托溴铵与沙美特罗替卡松联合吸入治疗慢性阻塞性肺疾病(COPD)患者的临床疗效。方法：2012年1月-2014年1月收治COPD患者60例，将其随机分成对照组和试验组，各30例，对照组给予沙美特罗替卡松治疗，试验组给予噻托溴铵与沙美特罗替卡松联合吸入治疗，对比两组临床疗效。结果：经过12周的治疗，试验组患者FEV1、FEV1/FVC指标均明显升高，试验组的临床症状改善明显更好，组间差异有统计学意义(P＜0.05)。结论：相对于沙美特罗替卡松单药治疗，噻托溴铵与沙美特罗替卡松联合治疗的疗效更好，患者肺功能、临床症状均得到明显的改善，治疗有效、安全，适于临床广泛应用。
목적：탐토새탁추안여사미특라체잡송연합흡입치료만성조새성폐질병(COPD)환자적림상료효。방법：2012년1월-2014년1월수치COPD환자60례，장기수궤분성대조조화시험조，각30례，대조조급여사미특라체잡송치료，시험조급여새탁추안여사미특라체잡송연합흡입치료，대비량조림상료효。결과：경과12주적치료，시험조환자FEV1、FEV1/FVC지표균명현승고，시험조적림상증상개선명현경호，조간차이유통계학의의(P＜0.05)。결론：상대우사미특라체잡송단약치료，새탁추안여사미특라체잡송연합치료적료효경호，환자폐공능、림상증상균득도명현적개선，치료유효、안전，괄우림상엄범응용。
Objective:To explore the curative effect of tiotropium bromide combined with seretide inhalation therapy for chronic obstructive pulmonary disease.Methods:60 patients with chronic obstructive pulmonary disease were selected from 2012 January to 2014 January,they were randomly divided into the control group and the experimental group with 30 cases in each group,the control group was given the seretide,and the experimental group was given tiotropium bromide combined with seretide inhalation therapy,we compared the clinical efficacy of the two groups.Results:After 12 weeks of treatment,in experimental group,FEV1,FEV1/FVC index were significantly elevated,in the experimental group,the clinical symptoms were improved obviously,differences between groups were significant(P<0.05).Conclusion:Compared with seretide single drug treatment,curative effect of tiotropium bromide combined with seretide inhalation therapy was better,the clinical symptoms were obviously improved,the treatment was effective and safe,and it was suitable for clinical application.