中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2015年
6期
4-7
,共4页
肺癌%靶向治疗%中医药%耐药性
肺癌%靶嚮治療%中醫藥%耐藥性
폐암%파향치료%중의약%내약성
Lung cancer%Targeted therapy%Traditional Chinese medicine%Drug resistance
目的：探讨非小细胞肺癌采用靶向治疗配合中医药辨证辨病相结合的思路和方法；方法：采用对肺癌的临床治疗，中医药配合西药靶向药物的手段，并综合分析、探索；结果：中医药养阴润肺化痰活血法可降低或消除靶向药物治疗非细胞肺癌的毒性和耐药性。结论：非小细胞肺癌采用靶向药物同时依据肺癌患者肺肾两虚、痰瘀内结的病理过程，采用养阴润肺化痰活血法，发挥着解毒增敏的作用，且直接治疗肿瘤，改善全身症状，提高生活质量，必能消除其耐药性。可能肺阴虚和“瘀”是EGFR-TKI基因耐药性的成因。
目的：探討非小細胞肺癌採用靶嚮治療配閤中醫藥辨證辨病相結閤的思路和方法；方法：採用對肺癌的臨床治療，中醫藥配閤西藥靶嚮藥物的手段，併綜閤分析、探索；結果：中醫藥養陰潤肺化痰活血法可降低或消除靶嚮藥物治療非細胞肺癌的毒性和耐藥性。結論：非小細胞肺癌採用靶嚮藥物同時依據肺癌患者肺腎兩虛、痰瘀內結的病理過程，採用養陰潤肺化痰活血法，髮揮著解毒增敏的作用，且直接治療腫瘤，改善全身癥狀，提高生活質量，必能消除其耐藥性。可能肺陰虛和“瘀”是EGFR-TKI基因耐藥性的成因。
목적：탐토비소세포폐암채용파향치료배합중의약변증변병상결합적사로화방법；방법：채용대폐암적림상치료，중의약배합서약파향약물적수단，병종합분석、탐색；결과：중의약양음윤폐화담활혈법가강저혹소제파향약물치료비세포폐암적독성화내약성。결론：비소세포폐암채용파향약물동시의거폐암환자폐신량허、담어내결적병리과정，채용양음윤폐화담활혈법，발휘착해독증민적작용，차직접치료종류，개선전신증상，제고생활질량，필능소제기내약성。가능폐음허화“어”시EGFR-TKI기인내약성적성인。
Objective:Exploration non-small cell lung cancer using targeted therapy with syndrome differentiation of traditional Chinese medicine disease combining the ideas and methods:method:the use of the clinical treatment of lung cancer, traditional Chinese medicine with western medicine means of targeted drugs, and comprehensive analysis, to explore: result: TCM Yin runfei phlegm and activating blood method can reduce or eliminate targeting the cell toxicity and drug resistance of lung cancer drug treatment.. conclusion:Non-small cell lung cancer using targeted drugs at the same time, according to the patients with lung cancer of lungs kidney deficiency, phlegm and blood stasis in the pathological process of Yin runfei phlegm and activating blood method, give play to the role of the sensitization of detoxification, and the direct treatment of the tumor, improve systemic symptom, improve their quality of life, will eliminate the resistance. Unlikely lung Yin deficiency and blood stasis is the cause of EGFR-TKI resistance genes.
