CAJ | 학술논문

目的：探讨分析自身免疫性肝炎患者临床和免疫学特点。方法回顾性分析2012年9月～2014年2月到我院实施诊治的13例自身免疫性肝炎患者，总结分析其临床和免疫学特点。结果13例自身免疫性肝炎患者中有8例是中年女性，发病高峰期为50岁左右，经肝功能检查显示胆红素和转氨酶存在异常，且免疫球蛋白 G 以及丙种球蛋白都比正常值高，其中有7例抗核抗体为阳性，临床症状主要表现为皮肤瘙痒、黄疸、纳差以及乏力。结论在自身免疫性肝炎临床诊治中，应结合患者临床表现以及相关免疫学指标等进行综合分析，合理诊断。
목적：탐토분석자신면역성간염환자림상화면역학특점。방법회고성분석2012년9월～2014년2월도아원실시진치적13례자신면역성간염환자，총결분석기림상화면역학특점。결과13례자신면역성간염환자중유8례시중년녀성，발병고봉기위50세좌우，경간공능검사현시담홍소화전안매존재이상，차면역구단백 G 이급병충구단백도비정상치고，기중유7례항핵항체위양성，림상증상주요표현위피부소양、황달、납차이급핍력。결론재자신면역성간염림상진치중，응결합환자림상표현이급상관면역학지표등진행종합분석，합리진단。
Objective To discussed the clinical and immunological characteristics of patients with autoimmune hepatitis. Methods Retrospectively analyzed 13 cases of patients with autoimmune hepatitis diagnosed and treated in our hospital from September 2012 to February 2014,then analyzed the clinical and immunological characteristics. Results 8 cases of these patients with autoimmune hepatitis were middle-aged women, and their morbidity peak is about 50 years old. Liver function tests showed their bilirubin and transaminas abnormal,immunoglobulin G and gamma globulin higher than normal,7 cases of these with antinuclear antibody positive,with itchy skin,jaundice,poor appetite,and lack of power as their main clinical symptoms. Conclusion Clinical diagnosis and treatment of autoimmune hepatitis should be comprehensive analysis and reasonable diagnosis with patients clinical manifestations and related immunological indexes.