中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2015年
12期
1864-1871
,共8页
王程越%赵远%杨曼%王树峰
王程越%趙遠%楊曼%王樹峰
왕정월%조원%양만%왕수봉
生物材料%口腔生物材料%纳米晶胶原人工骨%纳米生物材料%羟基磷灰石%骨缺损%骨引导%牙槽嵴%拔牙窝
生物材料%口腔生物材料%納米晶膠原人工骨%納米生物材料%羥基燐灰石%骨缺損%骨引導%牙槽嵴%拔牙窩
생물재료%구강생물재료%납미정효원인공골%납미생물재료%간기린회석%골결손%골인도%아조척%발아와
Colagen%Dental Implants%Bone Density%Alveolar Process
背景:拔牙后牙槽嵴的保存是一个重要的课题。新疆维吾尔自治区塔城地区边疆各县少数民族牙齿拔出后,由于就诊条件、地理条件等限制以及当地居民缺乏口腔保健意识等诸多因素,缺牙区长时间未及时修复导致牙槽嵴条件较差,因此寻找一种适合当地的且更有效的保存剩余牙槽嵴的方法,在当地有着较实用的临床价值。目的:探索纳米晶胶原人工骨用于新疆维吾尔自治区塔城地区哈萨克族人牙槽嵴保存的可行性。方法:采用自身配对设计,选取68例新疆维吾尔自治区塔城地区哈萨克族双侧拔牙患者,对就诊的双侧拔牙患者实验侧和对照侧的确定按“不平衡指数最小的分配原则”分组,实验侧拔牙窝植入纳米晶胶原人工骨,对照侧拔牙窝常规处理。植入后即刻及植入后3个月应用螺旋CT对植入区感兴趣区扫描,测量骨密度。结果与结论:植入后即刻,患者实验侧和对照侧 CT 图像可见拔牙窝清晰的轮廓,牙槽间隔可见;植入后3个月,患者实验侧和对照侧CT图像显示拔牙窝牙槽间隔影像模糊,CT值与周围牙槽突CT值接近,但实验侧植骨区骨充盈;且植入后3个月患者实验侧骨密度高于对照侧。说明纳米晶胶原人工骨用于新疆维吾尔自治区塔城地区哈萨克族患者牙槽嵴保存的临床效果较好。
揹景:拔牙後牙槽嵴的保存是一箇重要的課題。新疆維吾爾自治區塔城地區邊疆各縣少數民族牙齒拔齣後,由于就診條件、地理條件等限製以及噹地居民缺乏口腔保健意識等諸多因素,缺牙區長時間未及時脩複導緻牙槽嵴條件較差,因此尋找一種適閤噹地的且更有效的保存剩餘牙槽嵴的方法,在噹地有著較實用的臨床價值。目的:探索納米晶膠原人工骨用于新疆維吾爾自治區塔城地區哈薩剋族人牙槽嵴保存的可行性。方法:採用自身配對設計,選取68例新疆維吾爾自治區塔城地區哈薩剋族雙側拔牙患者,對就診的雙側拔牙患者實驗側和對照側的確定按“不平衡指數最小的分配原則”分組,實驗側拔牙窩植入納米晶膠原人工骨,對照側拔牙窩常規處理。植入後即刻及植入後3箇月應用螺鏇CT對植入區感興趣區掃描,測量骨密度。結果與結論:植入後即刻,患者實驗側和對照側 CT 圖像可見拔牙窩清晰的輪廓,牙槽間隔可見;植入後3箇月,患者實驗側和對照側CT圖像顯示拔牙窩牙槽間隔影像模糊,CT值與週圍牙槽突CT值接近,但實驗側植骨區骨充盈;且植入後3箇月患者實驗側骨密度高于對照側。說明納米晶膠原人工骨用于新疆維吾爾自治區塔城地區哈薩剋族患者牙槽嵴保存的臨床效果較好。
배경:발아후아조척적보존시일개중요적과제。신강유오이자치구탑성지구변강각현소수민족아치발출후,유우취진조건、지리조건등한제이급당지거민결핍구강보건의식등제다인소,결아구장시간미급시수복도치아조척조건교차,인차심조일충괄합당지적차경유효적보존잉여아조척적방법,재당지유착교실용적림상개치。목적:탐색납미정효원인공골용우신강유오이자치구탑성지구합살극족인아조척보존적가행성。방법:채용자신배대설계,선취68례신강유오이자치구탑성지구합살극족쌍측발아환자,대취진적쌍측발아환자실험측화대조측적학정안“불평형지수최소적분배원칙”분조,실험측발아와식입납미정효원인공골,대조측발아와상규처리。식입후즉각급식입후3개월응용라선CT대식입구감흥취구소묘,측량골밀도。결과여결론:식입후즉각,환자실험측화대조측 CT 도상가견발아와청석적륜곽,아조간격가견;식입후3개월,환자실험측화대조측CT도상현시발아와아조간격영상모호,CT치여주위아조돌CT치접근,단실험측식골구골충영;차식입후3개월환자실험측골밀도고우대조측。설명납미정효원인공골용우신강유오이자치구탑성지구합살극족환자아조척보존적림상효과교호。
BACKGROUND:It is an important issue of alveolar ridge preservation after tooth extraction. Because of the limited treatment and geographical conditions, lack of awareness of oral health, many local people in frontier areas in Xinjiang have poor alveolar ridge that is not of timely repair after tooth extraction. Thus, it is important to find a suitable local and efficient way to save the residual ridge, which has a more practical clinical value. OBJECTIVE:To investigate the feasibility of nano-colagen artificial bone used for alveolar ridge preservation in the Kazakh in Xinjiang Tacheng Region, China. METHODS: Sixty-eight Kazakh patients with bilateral extraction from Tacheng region, Xingjiang Uygur Autonomous Region, China were selected in a self-controled trial. According to the principle of a minimum alocation imbalance index, the experimental side and control side of extraction patients were confirmed. In the experimental side, nano-colagen artificial bone was implanted; while, conventional treatment was done in the control side. Multi-slice spiral CT was used to scan the regions of extraction interest to measure the relative gray value of alveolar bone mineral density immediately and 3 months after implantation. RESULTS AND CONCLUSION:Immediately after implantation, tooth extraction sockets were visible on CT images both in the experimental and control sides; but after 3 months, the extraction sockets became unclear on the CT images, and CT values were close to those of the surrounding alveolar process, but bone tissues were ful of the bone graft area in the experimental side. The alveolar bone mineral density was higher in the experimental side than the control side at 3 months after implantation. These findings indicate that the nano-colagen artificial bone has good clinical achievement in alveolar ridge preservation in the Kazakh in Xinjiang Tacheng Region.