临床和实验医学杂志
臨床和實驗醫學雜誌
림상화실험의학잡지
JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
2015年
7期
550-553
,共4页
带状疱疹%后遗肋间神经痛%活血通络止痛汤%中西医疗法
帶狀皰疹%後遺肋間神經痛%活血通絡止痛湯%中西醫療法
대상포진%후유륵간신경통%활혈통락지통탕%중서의요법
Postherpetic neuralgia%Dredging the collaterals to stop pain%Modified promoting Qi activating blood%Integration of tradition-al and western medicine
目的：观察自拟活血通络止痛汤加减治疗带状疱疹后遗肋间神经痛（PHN）的疗效。方法将84例 PHN患者随机分为观察组及对照组，两组各42例。对照组给予内服维生素 B1、盐酸多塞平片、甲钴胺片加外用1%双氯芬酸钠乳剂等常规治疗，观察组在常规治疗的基础上给予自拟活血通络止痛汤加减治疗。比较治疗后1周、2周、4周的数字疼痛评分量表（NRS）、皮肤病生活质量指数评分（DLQI）、匹兹堡睡眠质量评分（PSQI）及抑郁评分（SDS 评分），同时比较24 h 疼痛持续时间及24 h 总睡眠时间、疼痛缓解有效率。结果治疗后1周、2周、4周，两组的 NRS 评分、DLQI 评分、PSQI 评分及 SDS 评分均较治疗前降低（ P <0.05），观察组各项评分均低于对照组（ P <0.05）；治疗后各时间点观察组的24 h 疼痛持续时间明显少于对照组（ P <0.05），而24 h 总睡眠时间长于对照组（ P <0.05）；治疗后各时间点观察组的疼痛缓解有效率明显高于对照组（ P <0.05）。结论自拟活血通络止痛汤加减治疗带状疱疹后遗肋间神经痛的临床效果显著，能够明显改善患者的疼痛及抑郁症状，提高生活质量，可取的满意的综合疗效。
目的：觀察自擬活血通絡止痛湯加減治療帶狀皰疹後遺肋間神經痛（PHN）的療效。方法將84例 PHN患者隨機分為觀察組及對照組，兩組各42例。對照組給予內服維生素 B1、鹽痠多塞平片、甲鈷胺片加外用1%雙氯芬痠鈉乳劑等常規治療，觀察組在常規治療的基礎上給予自擬活血通絡止痛湯加減治療。比較治療後1週、2週、4週的數字疼痛評分量錶（NRS）、皮膚病生活質量指數評分（DLQI）、匹玆堡睡眠質量評分（PSQI）及抑鬱評分（SDS 評分），同時比較24 h 疼痛持續時間及24 h 總睡眠時間、疼痛緩解有效率。結果治療後1週、2週、4週，兩組的 NRS 評分、DLQI 評分、PSQI 評分及 SDS 評分均較治療前降低（ P <0.05），觀察組各項評分均低于對照組（ P <0.05）；治療後各時間點觀察組的24 h 疼痛持續時間明顯少于對照組（ P <0.05），而24 h 總睡眠時間長于對照組（ P <0.05）；治療後各時間點觀察組的疼痛緩解有效率明顯高于對照組（ P <0.05）。結論自擬活血通絡止痛湯加減治療帶狀皰疹後遺肋間神經痛的臨床效果顯著，能夠明顯改善患者的疼痛及抑鬱癥狀，提高生活質量，可取的滿意的綜閤療效。
목적：관찰자의활혈통락지통탕가감치료대상포진후유륵간신경통（PHN）적료효。방법장84례 PHN환자수궤분위관찰조급대조조，량조각42례。대조조급여내복유생소 B1、염산다새평편、갑고알편가외용1%쌍록분산납유제등상규치료，관찰조재상규치료적기출상급여자의활혈통락지통탕가감치료。비교치료후1주、2주、4주적수자동통평분량표（NRS）、피부병생활질량지수평분（DLQI）、필자보수면질량평분（PSQI）급억욱평분（SDS 평분），동시비교24 h 동통지속시간급24 h 총수면시간、동통완해유효솔。결과치료후1주、2주、4주，량조적 NRS 평분、DLQI 평분、PSQI 평분급 SDS 평분균교치료전강저（ P <0.05），관찰조각항평분균저우대조조（ P <0.05）；치료후각시간점관찰조적24 h 동통지속시간명현소우대조조（ P <0.05），이24 h 총수면시간장우대조조（ P <0.05）；치료후각시간점관찰조적동통완해유효솔명현고우대조조（ P <0.05）。결론자의활혈통락지통탕가감치료대상포진후유륵간신경통적림상효과현저，능구명현개선환자적동통급억욱증상，제고생활질량，가취적만의적종합료효。
Objective To observe the clinical effect of the method of Modified promoting Qi activating blood,dredging the collaterals to stop pain on the postherpetic neuralgia(PHN). Methods 84 patients with postherpetic neuralgia in this experiment totally were divided into treatment group and control group randomly. It has 42 cases per group. Control group accepted treatment with oral Vitamin B1,Mecobalamin and externalDoxepin and Diclofenac Sodium Cream. Treatment group accepted the same with control group and plus the method of Modified promoting Qi activating blood,dredging the collaterals. The score changes of the indexes of patients after treatments were observd for one weeK,two weeKs and four weeKs later,which included the scores of pain degree(NRS),sleep quality(PSQI),dermatology life quality index(DLQI)and self -rating depression scale(SDS). Results After treatment 1 weeK,2 weeKs,4 weeKs,the results of NRS,DLQI,PSQI and SDS in the observation groupwere significantly lower than the control group( P < 0. 05)in . After treatment,24 h duration of pain in the observation group at each time point was significantly less than the control group( P < 0. 05),and 24 h total sleep time was longer than the control group( P < 0. 05);each time point efficiency of pain relief in observation group was significantly higher than the control group( P < 0. 05). Conclusion The method of modified promoting Qi activating blood,dredging the collaterals to stop pain has good effect on treating postherpetic neuralgia. It can obviously re-duce the pain degree,improve the sleeping quality and the ability of worK or houseKeeping worK,and enhance the quality of their life.
