临床和实验医学杂志
臨床和實驗醫學雜誌
림상화실험의학잡지
JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
2015年
7期
598-600
,共3页
食管癌%超声内镜%染色内镜%窄带成像技术
食管癌%超聲內鏡%染色內鏡%窄帶成像技術
식관암%초성내경%염색내경%착대성상기술
Esophageal cancer%Endoscopic ultrasonography%Staining endoscopy%Narrow - band imaging
目的：研究超声内镜、染色法及窄带成像技术联合使用在诊断早期食管癌中的临床价值。方法选取2012年12月至2014年11月行普通白光胃镜检查怀疑食管黏膜病变的患者为研究对象，共424例，将患者按随机数字法分为观察组和对照组，各212例，对照组采用普通白光内镜进行检查，观察组在对照组检查基础上加用超声内镜、染色法及窄带成像技术检查，比较两组检查方法的灵敏度、特异度及准确率。结果观察组检出癌69例，癌检出率为32.55%；对照组检出癌72例，癌检出率为33.96%。两组癌检出率差异无统计学意义（ P >0.05）。观察组检测灵敏度、特异度、准确率分别为93.02%、82.84%、84.91%，对照组分别为82.86%、75.71%、76.89%。观察组检测方法准确率明显高于对照组，差异有统计学意义（ P <0.05）。但两组检测方法检测灵敏度、特异度无显著差异（ P >0.05）。结论普通白光内镜检查用于筛查早期食管癌具有较高的检出率、灵敏度及特异度，但对可疑病变患者可进一步行超声内镜、染色法联合窄带成像技术检查，以提高食管癌诊断的准确率。
目的：研究超聲內鏡、染色法及窄帶成像技術聯閤使用在診斷早期食管癌中的臨床價值。方法選取2012年12月至2014年11月行普通白光胃鏡檢查懷疑食管黏膜病變的患者為研究對象，共424例，將患者按隨機數字法分為觀察組和對照組，各212例，對照組採用普通白光內鏡進行檢查，觀察組在對照組檢查基礎上加用超聲內鏡、染色法及窄帶成像技術檢查，比較兩組檢查方法的靈敏度、特異度及準確率。結果觀察組檢齣癌69例，癌檢齣率為32.55%；對照組檢齣癌72例，癌檢齣率為33.96%。兩組癌檢齣率差異無統計學意義（ P >0.05）。觀察組檢測靈敏度、特異度、準確率分彆為93.02%、82.84%、84.91%，對照組分彆為82.86%、75.71%、76.89%。觀察組檢測方法準確率明顯高于對照組，差異有統計學意義（ P <0.05）。但兩組檢測方法檢測靈敏度、特異度無顯著差異（ P >0.05）。結論普通白光內鏡檢查用于篩查早期食管癌具有較高的檢齣率、靈敏度及特異度，但對可疑病變患者可進一步行超聲內鏡、染色法聯閤窄帶成像技術檢查，以提高食管癌診斷的準確率。
목적：연구초성내경、염색법급착대성상기술연합사용재진단조기식관암중적림상개치。방법선취2012년12월지2014년11월행보통백광위경검사부의식관점막병변적환자위연구대상，공424례，장환자안수궤수자법분위관찰조화대조조，각212례，대조조채용보통백광내경진행검사，관찰조재대조조검사기출상가용초성내경、염색법급착대성상기술검사，비교량조검사방법적령민도、특이도급준학솔。결과관찰조검출암69례，암검출솔위32.55%；대조조검출암72례，암검출솔위33.96%。량조암검출솔차이무통계학의의（ P >0.05）。관찰조검측령민도、특이도、준학솔분별위93.02%、82.84%、84.91%，대조조분별위82.86%、75.71%、76.89%。관찰조검측방법준학솔명현고우대조조，차이유통계학의의（ P <0.05）。단량조검측방법검측령민도、특이도무현저차이（ P >0.05）。결론보통백광내경검사용우사사조기식관암구유교고적검출솔、령민도급특이도，단대가의병변환자가진일보행초성내경、염색법연합착대성상기술검사，이제고식관암진단적준학솔。
Objective To study the clinic value of narrow - band imaging combined with staining and endoscopic ultrasonography in the diagnosis of early esophageal cancer. Methods Four hundred twenty - four patients with suspected esophageal mucosal lesions under conventional white light endoscopy were randomly assigned to the observation group and control group,212 cases in each group,the control group was examined with conventional white light endoscopy;in addition to the conventional white light endoscopy examination,the observation group was examined with narrow - band imaging combined with staining and endoscopic ultrasonography. The sensitivity,specificity and accuracy of the examinations between two groups were compared. Results Cancer was found in 69 cases(32. 55% )in observation group and in 72 cases(33. 96% )in con-trol group( P > 0. 05). The sensitivity,specificity and accuracy of detection were 93. 02% ,82. 84% ,and 84. 91% respectively,in observation group,while they were 82. 86% ,75. 71% ,and 76. 89% respectively in control group. The detection accuracy in observation group was signifi-cantly higher than the control group( P < 0. 05). No significant differences in sensitivity and specificity between two groups(( P > 0. 05). Con-clusion The combined use of narrow - band imaging,staining and endoscopic ultrasonography can significantly improve the accuracy of diagnosis of early esophageal cancer.
