中华检验医学杂志
中華檢驗醫學雜誌
중화검험의학잡지
CHINESE JOURNAL OF LABORATORY MEDICINE
2015年
2期
73-75
,共3页
微流体分析技术%核酸类%蛋白质类%药物评价,临床前%生物学标记
微流體分析技術%覈痠類%蛋白質類%藥物評價,臨床前%生物學標記
미류체분석기술%핵산류%단백질류%약물평개,림상전%생물학표기
Microfluidic analytical techniques%Nucleic acids%Proteins%Drug evaluation,preclinical%Biological markers
微流控芯片具有的精确流体控制、少量样品需求、快速反应及大规模集成的优势,使其成为临床诊断及疾病筛查的极具发展潜力的工具.集成化及自动化的微流控芯片系统目前已广泛用于核酸、蛋白及细胞等的检测及分析.近年来微流控芯片在核酸、蛋白质分析及细胞培养、分选及药物筛选等方面开展应用研究.微流控芯片可为生物标志物检测提供精确、高通量、易集成的研究及应用平台.
微流控芯片具有的精確流體控製、少量樣品需求、快速反應及大規模集成的優勢,使其成為臨床診斷及疾病篩查的極具髮展潛力的工具.集成化及自動化的微流控芯片繫統目前已廣汎用于覈痠、蛋白及細胞等的檢測及分析.近年來微流控芯片在覈痠、蛋白質分析及細胞培養、分選及藥物篩選等方麵開展應用研究.微流控芯片可為生物標誌物檢測提供精確、高通量、易集成的研究及應用平檯.
미류공심편구유적정학류체공제、소량양품수구、쾌속반응급대규모집성적우세,사기성위림상진단급질병사사적겁구발전잠력적공구.집성화급자동화적미류공심편계통목전이엄범용우핵산、단백급세포등적검측급분석.근년래미류공심편재핵산、단백질분석급세포배양、분선급약물사선등방면개전응용연구.미류공심편가위생물표지물검측제공정학、고통량、역집성적연구급응용평태.
Microfluidic chip exhibit a great promising development in clinical diagnosis and disease screening due to their advantages of precise controlling of fluid flow,requirement of mini amount sample,rapid reaction speed and convenient integration.A lot of demonstrations on the diagnostic applications related to genes,proteins,and cells have been reported because of their advantages associated with miniaturization and automation.Here,the applications and developments of on-chip nucleic acid amplification and analysis,protein analysis and detection,cell selection and cell drug screening were discussed.Microfluidic chip can provide an easy integration platform for biomarkers in a high throughput and accurate detection.
