CAJ | 학술논문

卵巢癌患者的静脉血栓发生率远高于其他妇科肿瘤，约20%以上的卵巢癌患者存在高凝状态。肿瘤可导致血液高凝状态，而凝血功能的过度激活也极大地促进肿瘤的进展，是影响患者预后的重要因素。近年来，高凝状态逐渐成为卵巢癌研究领域的新热点，本文将对卵巢癌患者高凝状态的形成机制、临床意义及相关治疗进展进行综述。
란소암환자적정맥혈전발생솔원고우기타부과종류，약20%이상적란소암환자존재고응상태。종류가도치혈액고응상태，이응혈공능적과도격활야겁대지촉진종류적진전，시영향환자예후적중요인소。근년래，고응상태축점성위란소암연구영역적신열점，본문장대란소암환자고응상태적형성궤제、림상의의급상관치료진전진행종술。
The incidence of venous thromboembolism in patients with ovarian cancer is much higher than other gynecologic cancers. Approximate 20%of ovarian cancer patients have hypercoagulable status during different phases of their disease. Ovarian cancer itself can induce hypercoagulability, but meanwhile the over activated coagulation system may promote disease progression. Coagulation system disorder is one of the most important prognostic factors in ovarian cancer. Recently, hypercoagulability becomes a hot spot in the ovarian cancer research ifeld. This article reviews the mechanism of hypercoagulability, its clinical implication and correlated treatment in ovarian cancer patients.