老年人血红蛋白含量与血压水平的相关性研究
노년인혈홍단백함량여혈압수평적상관성연구
Study on the relationship between hemoglobin level and blood pressure in elderly subjects
  • 万方数据
    临床内科杂志 림상내과잡지
    JOURNAL OF CLINICAL INTERNAL MEDICINE
    2015年 3期 170-173 ,共4页

    王坤伟%刘军%徐炯%丁和远%盛励%查兵兵%吴跃跃%黄新梅%王芳%陈灶萍%孙田歌%韩晓洁%洪洋%顾勇

    왕곤위%류군%서형%정화원%성려%사병병%오약약%황신매%왕방%진조평%손전가%한효길%홍양%고용

    老年人%血红蛋白%高血压 老年人%血紅蛋白%高血壓
    노년인%혈홍단백%고혈압
    Elderly%Hemoglobin%Hypertension
    目的：探讨老年人血红蛋白（Hb）含量与血压水平的相关性。方法以上海市闵行区江川社区2101例60岁以上体检者为研究对象。测量身高、体重、腰围（W）、臀围（H）和血压，检测 Hb、血脂、空腹血糖（FBG）、血肌酐（Cr）和丙氨酸转氨酶（ALT）。根据血压水平将其分为3组：正常血压组（＜120／80 mmHg，477例）、高血压前期组（120～139／80～89 mmHg，773例）、高血压组（≥140／90 mmHg，851例）。结果随着 Hb 含量逐渐升高，血压水平随之升高（P ＜0．05）。Pearson 相关分析显示，Hb 含量与体重、W、H、收缩压（SBP）、舒张压（DBP）、ALT、甘油三酯（TG）、FBG 及体重指数（BMI）均呈显著正相关，与高密度脂蛋白胆固醇呈显著负相关（P ＜0．01）。Logistic回归分析结果显示，在校正性别及心血管疾病危险因素后，Hb 最高四分位组发生高血压的危险性是最低四分位组的2．461倍（P ＜0．01）。多元逐步回归结果显示，Hb 是 SBP 和 DBP 升高的独立危险因素（P ＜0．01）。结论老年人群中随着 Hb 含量升高其血压水平随之升高，Hb 含量升高可能与高血压的发生及发展有关。
    목적：탐토노년인혈홍단백（Hb）함량여혈압수평적상관성。방법이상해시민행구강천사구2101례60세이상체검자위연구대상。측량신고、체중、요위（W）、둔위（H）화혈압，검측 Hb、혈지、공복혈당（FBG）、혈기항（Cr）화병안산전안매（ALT）。근거혈압수평장기분위3조：정상혈압조（＜120／80 mmHg，477례）、고혈압전기조（120～139／80～89 mmHg，773례）、고혈압조（≥140／90 mmHg，851례）。결과수착 Hb 함량축점승고，혈압수평수지승고（P ＜0．05）。Pearson 상관분석현시，Hb 함량여체중、W、H、수축압（SBP）、서장압（DBP）、ALT、감유삼지（TG）、FBG 급체중지수（BMI）균정현저정상관，여고밀도지단백담고순정현저부상관（P ＜0．01）。Logistic회귀분석결과현시，재교정성별급심혈관질병위험인소후，Hb 최고사분위조발생고혈압적위험성시최저사분위조적2．461배（P ＜0．01）。다원축보회귀결과현시，Hb 시 SBP 화 DBP 승고적독립위험인소（P ＜0．01）。결론노년인군중수착 Hb 함량승고기혈압수평수지승고，Hb 함량승고가능여고혈압적발생급발전유관。
    Objective To analyze the relationship between hemoglobin(Hb)level and blood pressure in elderly subjects.Methods This study was composed of 2 101 subjects of health examinations aged 60 years or above from Jiangchuan Community of Shanghai.The height,weight,waist(W),hip(H), blood pressure levels,Hb,blood lipid,fasting blood glucose(FBG),serum creatinine (Cr)and alanine transaminase(ALT)were measured.Subjects were classified into three groups according to blood pressure levels(normal blood pressure group:<120 /80 mmHg,n =477;prehypertension group:120 ~139 /80 ~89 mmHg,n =773;hypertension group:≥140 /90 mmHg,n =851).Results Blood pressure elevated with the gradually increasing Hb levels(P <0.05 ).Pearson correlation analysis showed that Hb significant positive correlated with weight,W,H,systolic blood pressure (SBP),diastolic blood pressure (DBP), ALT,triglyceride(TG),FBG and body mass index(BMI),but significant negative correlated with high density lipoprotein cholesterol(P <0.01 ).Logistic regression analysis showed that the highest quartile group of Hb in the risk of hypertension as the lowest quartile group was 2.461 times after adjusting for gender and cardiovascular disease risk factors.Multiple regression analysis showed that Hb was the inde-pendent risk factor of SBP and DBP.Conclusion For the subjects aged 60 years or above,blood pressure was elevated with the increasing Hb levels,elevated hemoglobin may be associated with the occurrence and development of hypertension.
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