岭南急诊医学杂志
嶺南急診醫學雜誌
령남급진의학잡지
LINGNAN JOURNAL OF EMERGENCY MEDICINE
2015年
1期
5-7
,共3页
冠心病%NT-proBNP水平%GRACE评分
冠心病%NT-proBNP水平%GRACE評分
관심병%NT-proBNP수평%GRACE평분
coronary heart disease%NT-pro BNP level%GRACE scores
目的：探讨冠心病患者氮末端脑钠素原（NT－proBNP）水平与全球急性冠状动脉事件注册评分（GRACE）的相关性。方法：以2011年6月至2013年6月在我院进行冠状动脉造影的冠心病患者116例为研究对象，按照冠心病的诊断标准分为稳定型冠心病组（SAP）78例和急性冠脉综合征组（ACS）38例，并以62例正常人为对照组（CON），测定各组外周血NT－proBNP，同时进行GRACE评分，对比两者间的相关性。结果：SAP组和ACS 的GRACE 评分和 NT－proBNP 水平均高于正常组，且 ACS 组显著高于 SAP 组（P＜0．05）。 GRACE 评分的中危组和高危组的NT－proBNP水平均显著高于低危组（P＜0．05）。冠心病患者 GRACE 评分与 NT－proBNP 水平间呈显著正相关（r＝0．473，P＜0．01）。结论：NT－proBNP水平与冠心病GRACE评分之间呈正相关。
目的：探討冠心病患者氮末耑腦鈉素原（NT－proBNP）水平與全毬急性冠狀動脈事件註冊評分（GRACE）的相關性。方法：以2011年6月至2013年6月在我院進行冠狀動脈造影的冠心病患者116例為研究對象，按照冠心病的診斷標準分為穩定型冠心病組（SAP）78例和急性冠脈綜閤徵組（ACS）38例，併以62例正常人為對照組（CON），測定各組外週血NT－proBNP，同時進行GRACE評分，對比兩者間的相關性。結果：SAP組和ACS 的GRACE 評分和 NT－proBNP 水平均高于正常組，且 ACS 組顯著高于 SAP 組（P＜0．05）。 GRACE 評分的中危組和高危組的NT－proBNP水平均顯著高于低危組（P＜0．05）。冠心病患者 GRACE 評分與 NT－proBNP 水平間呈顯著正相關（r＝0．473，P＜0．01）。結論：NT－proBNP水平與冠心病GRACE評分之間呈正相關。
목적：탐토관심병환자담말단뇌납소원（NT－proBNP）수평여전구급성관상동맥사건주책평분（GRACE）적상관성。방법：이2011년6월지2013년6월재아원진행관상동맥조영적관심병환자116례위연구대상，안조관심병적진단표준분위은정형관심병조（SAP）78례화급성관맥종합정조（ACS）38례，병이62례정상인위대조조（CON），측정각조외주혈NT－proBNP，동시진행GRACE평분，대비량자간적상관성。결과：SAP조화ACS 적GRACE 평분화 NT－proBNP 수평균고우정상조，차 ACS 조현저고우 SAP 조（P＜0．05）。 GRACE 평분적중위조화고위조적NT－proBNP수평균현저고우저위조（P＜0．05）。관심병환자 GRACE 평분여 NT－proBNP 수평간정현저정상관（r＝0．473，P＜0．01）。결론：NT－proBNP수평여관심병GRACE평분지간정정상관。
Objective:To explore the correlation between N-Terminal pro-B-type natriuretic peptide (NT-proBNP) levels and global acute coronary event registration evaluation (GRACE) in patients with coronary heart disease. Methods: 116 patients with coronary heart disease performed coronary angiography were selected as subjects from Jun 2011 to Jun 2013.They were divided into stable coronary group (SAP,n=78) and acute coronary syndrome (ACS,n=38) according to the diagnosis standards of coronary heart disease and healthy person as control group (CON,n=62),NT-proBNP of peripheral blood and GRACE scores were measured, and the correlation between the NT-proBNP and GRACE were analyzed. Results: The GRACE scores and NT-proBNP levels were significantly higher in both SAP group and ACS group than those in the CON group,and those ACS group were significantly higher than those in the SAP group (all P<0.05). The NT-proBNP levels were significantly higher in both middle and high risk groups were significantly higher than that in the low risk group (P<0.05) according GRACE scores (both P<0.05). There were positive correlation between the NT-proBNP levels and GRACE scores in patients with coronary heart disease (r=0.473,P<0.01). Conclusion:There are positive correlation between the NT-proBNP levels and GRACE scores in patients with coronary heart disease.
