国际放射医学核医学杂志
國際放射醫學覈醫學雜誌
국제방사의학핵의학잡지
INTERNATIONAL JOURNAL OF RADIATION MEDICINE AND NUCLEAR MEDICINE
2015年
1期
37-44
,共8页
甲状旁腺功能亢进症%99m锝甲氧基异丁基异腈%体层摄影术,发射型计算机,单光子%体层摄影术,X线计算机
甲狀徬腺功能亢進癥%99m锝甲氧基異丁基異腈%體層攝影術,髮射型計算機,單光子%體層攝影術,X線計算機
갑상방선공능항진증%99m득갑양기이정기이정%체층섭영술,발사형계산궤,단광자%체층섭영술,X선계산궤
Hyperparathyroidism%Technetium Tc 99m sestamibi%Tomography,emission-computed,single-photon%Tomography,X-ray computed
99Tcm-MIBI SPECT对甲状旁腺功能亢进症的术前诊断有较高的灵敏度，联合超声或CT能提高诊断和定位的准确率，尤其是对异位的甲状旁腺腺瘤。随着微创甲状旁腺切除术的发展，99Tcm-MIBI SPECT/CT在术前准确定位上的价值日益凸显。甲状旁腺病灶的大小、生化指标等因素会影响99Tcm-MIBI显像的灵敏度和定位准确率。对于部分难以准确诊断和定位的甲状旁腺功能亢进症患者，11C-蛋氨酸PET/CT、四维CT、术中放射导航等是目前的研究热点和发展方向。
99Tcm-MIBI SPECT對甲狀徬腺功能亢進癥的術前診斷有較高的靈敏度，聯閤超聲或CT能提高診斷和定位的準確率，尤其是對異位的甲狀徬腺腺瘤。隨著微創甲狀徬腺切除術的髮展，99Tcm-MIBI SPECT/CT在術前準確定位上的價值日益凸顯。甲狀徬腺病竈的大小、生化指標等因素會影響99Tcm-MIBI顯像的靈敏度和定位準確率。對于部分難以準確診斷和定位的甲狀徬腺功能亢進癥患者，11C-蛋氨痠PET/CT、四維CT、術中放射導航等是目前的研究熱點和髮展方嚮。
99Tcm-MIBI SPECT대갑상방선공능항진증적술전진단유교고적령민도，연합초성혹CT능제고진단화정위적준학솔，우기시대이위적갑상방선선류。수착미창갑상방선절제술적발전，99Tcm-MIBI SPECT/CT재술전준학정위상적개치일익철현。갑상방선병조적대소、생화지표등인소회영향99Tcm-MIBI현상적령민도화정위준학솔。대우부분난이준학진단화정위적갑상방선공능항진증환자，11C-단안산PET/CT、사유CT、술중방사도항등시목전적연구열점화발전방향。
99Tcm-MIBI SPECT exhibited high sensitivity in hyperparathyroidism. Combination of ultrasound or CT can raise the diagnostic and location accuracy, especially in ectopic parathyroid adenoma. With the development of minimally invasive parathyroidectomy, the value of 99Tcm-MIBI SPECT/CT in preoperative location accuracy stands out. Many factors such as size of the gland lesions and biochemical indexes affect the sensitivity and location accuracy of 99Tcm-MIBI scintigraphy. For the negative imaging hyperparathyroidism patients, 11C-methionine PET/CT, 4D-CT and intraoperative radiation navigation is current research hot spot and development orientation.
