中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2015年
3期
278-281
,共4页
刘正豪%邓跃飞%郑眉光%李忠军%李超
劉正豪%鄧躍飛%鄭眉光%李忠軍%李超
류정호%산약비%정미광%리충군%리초
脑转移瘤%早期诊断%显微外科手术
腦轉移瘤%早期診斷%顯微外科手術
뇌전이류%조기진단%현미외과수술
Brain metastasis%Early diagnosis%Microsurgical treatment
目的 探讨脑转移瘤的早期诊断及手术治疗经验,提高治疗效果. 方法 回顾性分析中山大学孙逸仙纪念医院神经外科自2003年1月至2013年12月手术治疗的80例脑转移瘤患者的临床资料,分析其早期诊断、治疗及生存情况. 结果 无症状定期头颅CT或MRI增强扫描早期发现12例(15％).手术后2周神经系统症状完全消失32例(40.0％)、明显缓解40例(50.0％)、无缓解或加重6例(7.5％)、死亡2例(2.5％).术后早期死亡(≤6个月)8例(10.3％),均为合并有颅外其他部位转移瘤患者.1年生存率为60.3％(47/78),2年生存率为34.6％(27/78),3年生存率为20.5％(16/78),存活≥5年5例6.4％(5/78),中位生存时间为17个月.存活≥3年的16例中,9例为早期发现的无症状患者. 结论 原发恶性肿瘤切除术后定期行头颅CT或MRI增强扫描检查是早期诊断脑转移瘤的有效手段;手术可改善脑转移瘤患者生存质量和延长患者生存期.
目的 探討腦轉移瘤的早期診斷及手術治療經驗,提高治療效果. 方法 迴顧性分析中山大學孫逸仙紀唸醫院神經外科自2003年1月至2013年12月手術治療的80例腦轉移瘤患者的臨床資料,分析其早期診斷、治療及生存情況. 結果 無癥狀定期頭顱CT或MRI增彊掃描早期髮現12例(15％).手術後2週神經繫統癥狀完全消失32例(40.0％)、明顯緩解40例(50.0％)、無緩解或加重6例(7.5％)、死亡2例(2.5％).術後早期死亡(≤6箇月)8例(10.3％),均為閤併有顱外其他部位轉移瘤患者.1年生存率為60.3％(47/78),2年生存率為34.6％(27/78),3年生存率為20.5％(16/78),存活≥5年5例6.4％(5/78),中位生存時間為17箇月.存活≥3年的16例中,9例為早期髮現的無癥狀患者. 結論 原髮噁性腫瘤切除術後定期行頭顱CT或MRI增彊掃描檢查是早期診斷腦轉移瘤的有效手段;手術可改善腦轉移瘤患者生存質量和延長患者生存期.
목적 탐토뇌전이류적조기진단급수술치료경험,제고치료효과. 방법 회고성분석중산대학손일선기념의원신경외과자2003년1월지2013년12월수술치료적80례뇌전이류환자적림상자료,분석기조기진단、치료급생존정황. 결과 무증상정기두로CT혹MRI증강소묘조기발현12례(15％).수술후2주신경계통증상완전소실32례(40.0％)、명현완해40례(50.0％)、무완해혹가중6례(7.5％)、사망2례(2.5％).술후조기사망(≤6개월)8례(10.3％),균위합병유로외기타부위전이류환자.1년생존솔위60.3％(47/78),2년생존솔위34.6％(27/78),3년생존솔위20.5％(16/78),존활≥5년5례6.4％(5/78),중위생존시간위17개월.존활≥3년적16례중,9례위조기발현적무증상환자. 결론 원발악성종류절제술후정기행두로CT혹MRI증강소묘검사시조기진단뇌전이류적유효수단;수술가개선뇌전이류환자생존질량화연장환자생존기.
Objective To investigate the experience of early diagnosis and surgical treatment of brain metastases to improve the therapy effect.Methods Retrospective analysis was performed on clinical data of 80 patients with brain metastases,received surgical treatment in our hospital from January 2003 to December 2013.The early diagnosis,treatment and survival of these patients were analyzed.Results Asymptomatic regularly head computerized tomography (CT) or enhanced magnetic resonance imaging (MRI) found 12 patients (15％).Two weeks after surgery,32 patients (40.0％) had totally disappeared neurological disorders,40 (50.0％) had obvious relief,6 (7.5％) were without relieved or even aggravated,and 2 (2.5％) were dead.Eight patients (10.0％) who combined with extracranial metastases died within 6 months of surgery.The one-year survival rate was 60.3％ (47/78),two-year survival rate was 34.6％ (27/78),three-year survival rate was 20.5％ (16/78) and five-year survival rate was 6.4％ (5/78);the median survival was 17 months.In 16 patients of survival more than 3 years,9 were the early-detection asymptomatic patients.Conclusion After resection of primary malignant tumor,the periodical enhanced head CT or MRI are effective measures for early diagnosis of brain metastases; surgical treatment can improve the survival quality and prolong survival time of patients with brain metastases.
