CAJ | 학술논문

目的探讨单光子发射计算机断层显像术(SPECT)对评价改良脑-硬膜-动脉血管联通术(EDAS)治疗烟雾病(MMD)疗效的应用价值. 方法广州军区广州总医院神经外科自2011年1月至2013年12月采用改良脑-硬膜-动脉血管联通术(EDAS)治疗MMD患者36例,其中缺血型MMD患者29例,出血型MMD患者7例,对患者术前及术后行单光子发射计算机断层显像术(SPECT)检查,比较手术侧大脑半球脑血流量的变化. 结果 36例MMD患者共41侧大脑半球行EDAS术,术后23侧大脑半球术后的脑血流量较术前增加,总体改善率为56.1％(23/41),其中缺血型MMD患者中20测大脑半球术后的脑血流量较术前增加,改善率为58.8％(20/34),出血型MMD患者中3测大脑半球术后的脑血流量较术前增加,改善率为42.9％(3/7). 结论改良EDAS治疗MMD术后脑组织血流量明显改善,证明改良EDAS治疗MMD疗效确切.
목적 탐토단광자발사계산궤단층현상술(SPECT)대평개개량뇌-경막-동맥혈관련통술(EDAS)치료연무병(MMD)료효적응용개치. 방법 엄주군구엄주총의원신경외과자2011년1월지2013년12월채용개량뇌-경막-동맥혈관련통술(EDAS)치료MMD환자36례,기중결혈형MMD환자29례,출혈형MMD환자7례,대환자술전급술후행단광자발사계산궤단층현상술(SPECT)검사,비교수술측대뇌반구뇌혈류량적변화. 결과 36례MMD환자공41측대뇌반구행EDAS술,술후23측대뇌반구술후적뇌혈류량교술전증가,총체개선솔위56.1％(23/41),기중결혈형MMD환자중20측대뇌반구술후적뇌혈류량교술전증가,개선솔위58.8％(20/34),출혈형MMD환자중3측대뇌반구술후적뇌혈류량교술전증가,개선솔위42.9％(3/7). 결론 개량EDAS치료MMD술후뇌조직혈류량명현개선,증명개량EDAS치료MMD료효학절.
Objective To evaluate the effects of modified encephalo-duro-arterio-synangiosis (EDAS) on Moyamoya diseases (MMD) by single photon emission tomography (SPECT).Methods Thirty-six patients with MMD (29 with ischemic MMD and 7 with hemorrhagic MMD),admitted to our hospital from January 2011 to December 2013 and treated by modified EDAS,were chosen in our study;all the patients were followed up by SPECT,and the images changes before and after modified EDAS were compared.Results In the 36 MMD patients,41 hemisheres were treated by modified EDAS; the total improvement rate was 56.1％ (23/41),enjoying increased cerebral blood flow after EDAS; in ischemic MMD patients,the total improvement rate was 58.8％ (20/34),while those was 42.9％ (3/7) in hemorrhagic MMD patients.Conclusion The cerebral blood flow is improved obviously when MMD is treated by modified EDAS,especial on ischemic MMD patients.