按摩与康复医学
按摩與康複醫學
안마여강복의학
Chinese Manipulation & Rehabilitation Medicine
2015年
7期
10-11
,共2页
脑梗死后出血性转化(HT)%溶栓%机制%预后%组织型纤溶酶原激活物(t-PA)%细胞外基质%基质金属蛋白酶(MMP)
腦梗死後齣血性轉化(HT)%溶栓%機製%預後%組織型纖溶酶原激活物(t-PA)%細胞外基質%基質金屬蛋白酶(MMP)
뇌경사후출혈성전화(HT)%용전%궤제%예후%조직형섬용매원격활물(t-PA)%세포외기질%기질금속단백매(MMP)
hemorrhagic transformation (HT)%thrombolysis%mechanism%prognosis%tissue type plasminogen activator (t-PA)%extracellular matrix%matrix metalloproteinase (MMP)
临床脑梗死的致残率与病死率非常高,通过溶栓治疗可以有效改善患者的神经功能,促进脑部神经功能恢复,但会诱发脑梗死后出血性转化(HT),加重神经功能障碍损伤,增加病死率。本文综述HT发病机制、类型及相关预后,探讨溶栓剂组织型纤溶酶原激活物(t-PA)对HT的影响。
臨床腦梗死的緻殘率與病死率非常高,通過溶栓治療可以有效改善患者的神經功能,促進腦部神經功能恢複,但會誘髮腦梗死後齣血性轉化(HT),加重神經功能障礙損傷,增加病死率。本文綜述HT髮病機製、類型及相關預後,探討溶栓劑組織型纖溶酶原激活物(t-PA)對HT的影響。
림상뇌경사적치잔솔여병사솔비상고,통과용전치료가이유효개선환자적신경공능,촉진뇌부신경공능회복,단회유발뇌경사후출혈성전화(HT),가중신경공능장애손상,증가병사솔。본문종술HT발병궤제、류형급상관예후,탐토용전제조직형섬용매원격활물(t-PA)대HT적영향。
The clinical morbidity and mortality of cerebral infarction are very high, thrombolytic therapy can effectively improve the neural function, promote the recovery of brain function, but also may hemorrhagic transformation (HT), aggravate the injury of nerve dysfunction and increase mor-tality. This paper summarizes the pathogenesis type and prognosis of HT and investigates the effect of thrombolytic tissue type plasminogen activator (t-PA) on HT.