中华地方病学杂志
中華地方病學雜誌
중화지방병학잡지
Chinese Journal of Endemiology
2015年
3期
208-212
,共5页
碘%甲状腺疾病%住院率%疾病谱%构成
碘%甲狀腺疾病%住院率%疾病譜%構成
전%갑상선질병%주원솔%질병보%구성
Iodine%Thyroid disease%Hospitalization rate%Disease spectrum%Composition
目的 分析江苏省连云港市2002-2010年甲状腺疾病住院构成的变化,了解连云港市在实施普遍食盐加碘(USI)过程中碘摄入对甲状腺疾病的影响,为科学防治甲状腺疾病提供流行病学依据.方法 收集2002-2010年连云港市及所属县二级以上医疗机构甲状腺疾病住院患者资料,同时收集连云港市5个县区的居民户碘盐监测结果,分析甲状腺疾病构成的变化,以及甲状腺疾病与碘盐的关系.结果 ①共收集3 559名甲状腺疾病住院患者,男、女性别比为1:3.36.平均年龄为(46.81±14.94)岁,40～ 60岁是高峰年龄.②甲状腺肿大、甲状腺功能亢进、甲状腺炎、甲状腺功能减退和其他甲状腺疾患的构成比分别为41.64％(1 482/3 559)、40.07％(1 426/3 559)、6.83％(243/3 559)、6.21％(221/3 559)和5.25％(187/3 559).③2002-2010年,甲状腺疾病总住院率呈上升趋势(x2=460.12,P＜0.01);甲状腺功能减退、甲状腺肿大、甲状腺功能亢进、甲状腺炎和其他甲状腺疾患的住院率也均呈现上升趋势(x2=50.54、281.91、85.15、19.51、65.01,P均＜0.01).④在住院的甲状腺疾病患者当中,2002-2006年,甲状腺功能亢进的构成比最大,范围为42.03％(124/295) ～ 53.02％(114/215),其次为甲状腺肿大,构成比范围为34.55％(142/411)～39.25％(73/186);2007-2010年,甲状腺肿大的构成比最大,范围为42.11％(232/551)～49.57％(291/587),其次为甲状腺功能亢进,范围为33.05％(194/587) ～ 40.47％(223/551).⑤2002-2010年居民盐碘覆盖率、合格碘盐食用率均呈现上升趋势(x2=183.75、211.99,P均＜0.01).⑥甲状腺疾病总住院率、甲状腺功能减退住院率、甲状腺肿大住院率、其他甲状腺疾患住院率和碘盐覆盖率、合格碘盐食用率之间均存在正相关关系(L=0.83、0.93,0.82、0.87,0.83、0.93,0.74、0.91,P均＜0.05).⑦甲状腺功能亢进与合格碘盐食用率呈正相关关系(rs=0.72,P＜0.05).结论 2002-2010年,连云港市甲状腺疾病住院患者的疾病构成发生了变化,碘摄入对甲状腺疾病住院率的变化有一定影响.
目的 分析江囌省連雲港市2002-2010年甲狀腺疾病住院構成的變化,瞭解連雲港市在實施普遍食鹽加碘(USI)過程中碘攝入對甲狀腺疾病的影響,為科學防治甲狀腺疾病提供流行病學依據.方法 收集2002-2010年連雲港市及所屬縣二級以上醫療機構甲狀腺疾病住院患者資料,同時收集連雲港市5箇縣區的居民戶碘鹽鑑測結果,分析甲狀腺疾病構成的變化,以及甲狀腺疾病與碘鹽的關繫.結果 ①共收集3 559名甲狀腺疾病住院患者,男、女性彆比為1:3.36.平均年齡為(46.81±14.94)歲,40～ 60歲是高峰年齡.②甲狀腺腫大、甲狀腺功能亢進、甲狀腺炎、甲狀腺功能減退和其他甲狀腺疾患的構成比分彆為41.64％(1 482/3 559)、40.07％(1 426/3 559)、6.83％(243/3 559)、6.21％(221/3 559)和5.25％(187/3 559).③2002-2010年,甲狀腺疾病總住院率呈上升趨勢(x2=460.12,P＜0.01);甲狀腺功能減退、甲狀腺腫大、甲狀腺功能亢進、甲狀腺炎和其他甲狀腺疾患的住院率也均呈現上升趨勢(x2=50.54、281.91、85.15、19.51、65.01,P均＜0.01).④在住院的甲狀腺疾病患者噹中,2002-2006年,甲狀腺功能亢進的構成比最大,範圍為42.03％(124/295) ～ 53.02％(114/215),其次為甲狀腺腫大,構成比範圍為34.55％(142/411)～39.25％(73/186);2007-2010年,甲狀腺腫大的構成比最大,範圍為42.11％(232/551)～49.57％(291/587),其次為甲狀腺功能亢進,範圍為33.05％(194/587) ～ 40.47％(223/551).⑤2002-2010年居民鹽碘覆蓋率、閤格碘鹽食用率均呈現上升趨勢(x2=183.75、211.99,P均＜0.01).⑥甲狀腺疾病總住院率、甲狀腺功能減退住院率、甲狀腺腫大住院率、其他甲狀腺疾患住院率和碘鹽覆蓋率、閤格碘鹽食用率之間均存在正相關關繫(L=0.83、0.93,0.82、0.87,0.83、0.93,0.74、0.91,P均＜0.05).⑦甲狀腺功能亢進與閤格碘鹽食用率呈正相關關繫(rs=0.72,P＜0.05).結論 2002-2010年,連雲港市甲狀腺疾病住院患者的疾病構成髮生瞭變化,碘攝入對甲狀腺疾病住院率的變化有一定影響.
목적 분석강소성련운항시2002-2010년갑상선질병주원구성적변화,료해련운항시재실시보편식염가전(USI)과정중전섭입대갑상선질병적영향,위과학방치갑상선질병제공류행병학의거.방법 수집2002-2010년련운항시급소속현이급이상의료궤구갑상선질병주원환자자료,동시수집련운항시5개현구적거민호전염감측결과,분석갑상선질병구성적변화,이급갑상선질병여전염적관계.결과 ①공수집3 559명갑상선질병주원환자,남、녀성별비위1:3.36.평균년령위(46.81±14.94)세,40～ 60세시고봉년령.②갑상선종대、갑상선공능항진、갑상선염、갑상선공능감퇴화기타갑상선질환적구성비분별위41.64％(1 482/3 559)、40.07％(1 426/3 559)、6.83％(243/3 559)、6.21％(221/3 559)화5.25％(187/3 559).③2002-2010년,갑상선질병총주원솔정상승추세(x2=460.12,P＜0.01);갑상선공능감퇴、갑상선종대、갑상선공능항진、갑상선염화기타갑상선질환적주원솔야균정현상승추세(x2=50.54、281.91、85.15、19.51、65.01,P균＜0.01).④재주원적갑상선질병환자당중,2002-2006년,갑상선공능항진적구성비최대,범위위42.03％(124/295) ～ 53.02％(114/215),기차위갑상선종대,구성비범위위34.55％(142/411)～39.25％(73/186);2007-2010년,갑상선종대적구성비최대,범위위42.11％(232/551)～49.57％(291/587),기차위갑상선공능항진,범위위33.05％(194/587) ～ 40.47％(223/551).⑤2002-2010년거민염전복개솔、합격전염식용솔균정현상승추세(x2=183.75、211.99,P균＜0.01).⑥갑상선질병총주원솔、갑상선공능감퇴주원솔、갑상선종대주원솔、기타갑상선질환주원솔화전염복개솔、합격전염식용솔지간균존재정상관관계(L=0.83、0.93,0.82、0.87,0.83、0.93,0.74、0.91,P균＜0.05).⑦갑상선공능항진여합격전염식용솔정정상관관계(rs=0.72,P＜0.05).결론 2002-2010년,련운항시갑상선질병주원환자적질병구성발생료변화,전섭입대갑상선질병주원솔적변화유일정영향.
Objective To analyze the changes in the composition of hospitalization of thyroid disease in Lianyungang City from 2002 to 2010,to learn the impact of iodine intake on thyroid disease in Lianyungang City after implementing universal salt iodization (USI),and to get epidemiologic evidence for prevention and control of iodine deficiency disorders scientifically.Methods Medical reports of the patients with thyroid disease were collected from hospitals at county level and above institutions in Lianyungang City from 2002 to 2010.Monitoring results of household iodized salt were also collected from five counties (districts) in Lianyungang City.The changes in the composition of hospitalization of thyroid disease were analyzed,and the relationship between thyroid disease and iodized salt was studied.Results ① A total of 3 559 patients with thyroid disease were enrolled in the study,the ratio between male and female was 1 ∶ 3.36.Mean age was (46.81 ± 14.94) years old and the peak age was from 40 to 60 years old.② Among the hospitalized patients with thyroid disease,the proportion of goiter patients,hyperthyroidism patients,thyroiditis patients,hypothyroidism and other thyroid disorders was 41.64％ (1 482/3 559),40.07％ (1 426/3 559),6.83％ (243/3 559),6.21％ (221/3 559) and 5.25％ (187/3 559),respectively.③In 2002-2010,the hospitalization rate of thyroid disease showed an upward trend (x2 =460.12,P＜ 0.01),and the hospitalization rates of hypothyroidism,goiter,hyperthyroidism,thyroiditis and other thyroid disorders were all increased year by year (x2 =50.54,281.91,85.15,19.51 and 65.01,all P ＜ 0.01).④From 2002 to 2006,among the patients with thyroid disease,the proportion of hyperthyroidism was the highest,and the range of values was from 42.03％ (124/295) to 53.02％ (114/215).Followed by goiter,and the range of values was from 34.55％ (142/411) to 39.25％ (73/186).From 2007 to 2010,the proportion of goiter became the highest,and the range of values was from 42.11％ (232/551) to 49.57％ (291/587).Followed by hyperthyroidism,and the range of values was from 33.05％ (194/587) to 40.47％ (223/551).⑤From 2002 to 2010,the coverage of iodized salt and the consumption rate of qualified iodized salt both increased year by year (x2 =183.75,211.99,all P ＜ 0.01).⑥There were positive correlations between the hospitalization rates of thyroid disease,hypothyroidism,goiter,other thyroid disorders and the coverage of iodized salt,and the consumption rate of qualified iodized salt (rs =0.83,0.93,0.82,0.87,0.83,0.93,0.74 and 0.91,all P ＜ 0.05).⑦There was a positive correlation between the hospitalization rate of hyperthyroidism and the consumption rate of qualified iodized salt (rs =0.72,P ＜ 0.05).Conclusions There are some changes in the composition of hospitalization of thyroid disease in Lianyungang city from 2002 to 2010.Iodine intake may affect the hospitalization rate of thyroid disease.
