CAJ | 학술논문

人类白细胞抗原(HLA)是人类基因组中多态性最高的基因复合体.其编码产物HLA分子具有抗原提呈功能,在机体免疫应答中起到重要作用.大量研究表明,HLA分子与许多自身免疫性疾病和病毒感染性疾病密切相关.深入研究HLA分子与疾病相关性的内在机制将会为人类攻克这些顽疾带来希望.
인류백세포항원(HLA)시인류기인조중다태성최고적기인복합체.기편마산물HLA분자구유항원제정공능,재궤체면역응답중기도중요작용.대량연구표명,HLA분자여허다자신면역성질병화병독감염성질병밀절상관.심입연구HLA분자여질병상관성적내재궤제장회위인류공극저사완질대래희망.
Human leukocyte antigen (HLA)is the highest pleomorphic gene complex in human genome.Its encoding product (HLA molecule) has the function of antigen presentation,plays an important role in immune response.A large number of studies show that HLA molecules are closely related with many autoimmune diseases and virus infectious diseases.So in-depth study of the intrinsic mechanism between HLA molecules and HLA-related diseases would bring the hope to overcome these diseases.