CAJ | 학술논문

目的观察健康比格犬左室心肌三维峰值位移(3D-D)、径向位移(RD)、纵向位移(LD)变化,量化评价健康比格犬左室心肌位移的力学变化特征,探讨心肌位移参数的临床应用价值.方法 10只健康比格犬开胸模型,分别采集一个完整心动周期的实时全容积灰阶图像,应用斑点追踪成像技术测量左室心肌整体和各节段3D-D、RD和LD的峰值变化,分析3D-D、RD和LD之间的差异性及相关性.结果结果①左室心肌各节段3D-D与RD之间比较差异无统计学意义(P＞0.05);左室心肌各节段3D-D与LD之间比较差异具有显著统计学意义(P＜0.01);左室心肌各节段RD与LD之间比较差异具有显著统计学意义(P＜0.01),左室心肌各节段LD小于3D-D和RD,差异具有显著统计学意义(P＜0.01).②左室心肌整体3D-D与RD之间比较差异无统计学意义(P＞0.05);左室心肌整体3D-D与LD之间比较差异具有显著统计学意义(P＜0.01);左室心肌整体RD与LD之间比较差异具有显著统计学意义(P＜0.01);左室心肌整体LD小于3D-D和RD,差异具有显著统计学意义(P＜0.01).③左室心肌大多数节段3D-D与RD具有显著相关性(P＜0.01),仅中侧壁和尖侧壁具有相关性(P＜0.05);左室心肌3D-D与LD相关性分析,仅底前间隔、底下壁、中前壁、中前间隔、尖下壁、尖侧壁具有相关性(P＜0.05),其余节段之间不具有相关性(P＞0.05);左室心肌RD与LD相关性分析,仅底前间隔、底下壁、中前壁、尖间隔、尖下壁、尖侧壁具有相关性(P＜0.05),其余节段之间不具有相关性(P＞0.05).结论左室心肌3D-D与RD比较无明显差异同时密切相关,3D-D能够准确反映左室心肌实际的运动轨迹,RD是左室三维结构形变和力学变化的主要表现形式,RD比LD更能反映左室心肌的有效运动.
목적 관찰건강비격견좌실심기삼유봉치위이(3D-D)、경향위이(RD)、종향위이(LD)변화,양화평개건강비격견좌실심기위이적역학변화특정,탐토심기위이삼수적림상응용개치.방법 10지건강비격견개흉모형,분별채집일개완정심동주기적실시전용적회계도상,응용반점추종성상기술측량좌실심기정체화각절단3D-D、RD화LD적봉치변화,분석3D-D、RD화LD지간적차이성급상관성.결과 결과①좌실심기각절단3D-D여RD지간비교차이무통계학의의(P＞0.05);좌실심기각절단3D-D여LD지간비교차이구유현저통계학의의(P＜0.01);좌실심기각절단RD여LD지간비교차이구유현저통계학의의(P＜0.01),좌실심기각절단LD소우3D-D화RD,차이구유현저통계학의의(P＜0.01).②좌실심기정체3D-D여RD지간비교차이무통계학의의(P＞0.05);좌실심기정체3D-D여LD지간비교차이구유현저통계학의의(P＜0.01);좌실심기정체RD여LD지간비교차이구유현저통계학의의(P＜0.01);좌실심기정체LD소우3D-D화RD,차이구유현저통계학의의(P＜0.01).③좌실심기대다수절단3D-D여RD구유현저상관성(P＜0.01),부중측벽화첨측벽구유상관성(P＜0.05);좌실심기3D-D여LD상관성분석,부저전간격、저하벽、중전벽、중전간격、첨하벽、첨측벽구유상관성(P＜0.05),기여절단지간불구유상관성(P＞0.05);좌실심기RD여LD상관성분석,부저전간격、저하벽、중전벽、첨간격、첨하벽、첨측벽구유상관성(P＜0.05),기여절단지간불구유상관성(P＞0.05).결론 좌실심기3D-D여RD비교무명현차이동시밀절상관,3D-D능구준학반영좌실심기실제적운동궤적,RD시좌실삼유결구형변화역학변화적주요표현형식,RD비LD경능반영좌실심기적유효운동.
Objective To evaluate the changes of left ventricular myocardial peak 3-dimensional displacement(3D-D),radial displacement(RD) and longitudinal displacement(LD) during baseline patterns,and provide a reliable and appropriate mechanical database for myocardial structure and function.Methods Left ventricular 3D full volumetric real-time imaging in open-chest Beagle canine models(n =10) were acquired in a complete cardiac cycle.The 3D-D,RD and LD for differences and rules were calculated and analyzed by speckle tracking imaging.Results ① There were not difference between 3D-D and RD at baseline patterns with all segments(P ＞0.05).There were significant difference between 3D-D and LD at baseline patterns with all segments (P ＜0.01).There were significant difference between LD and RD at baseline patterns with all segments(P ＜0.01).② There were not difference between 3D-D and RD at baseline patterns with the global(P ＞0.05).There were significant difference between 3D-D and LD at baseline patterns with the global(P ＜ 0.01).There were significant difference between LD and RD at baseline patterns with the global(P ＜0.01).③ There were significant correlation between 3D-D and the most segments of RD(P ＜0.01).There were correlation between 3D-D and the partly segments of LD (P ＜ 0.05).There were correlation between the partly segments of RD and LD(P ＜0.05).Conclusions Echocardiographic study of left ventricular 3D-D can actually reveal myocardial mechanics and strcture during baseline patterns.3D-D can accurately reflect left ventricular motion condition.The changes of myocardial mechanics mainly depends on the radial motion.Left ventricular RD can be more accurately reflection on myocardial motion state than LD.