CAJ | 학술논문

目的对临床证实由巨细胞病毒(CMV)感染所致的脑性瘫痪的患儿进行临床特点分析.方法对51例明确由CMV感染的脑性瘫痪进行相关临床症状分析,找出其特性,并分析其发生的原因.结果在CMV感染所致的脑性瘫痪的临床症状与其他原因所致的脑瘫相似,但其他原因所致的脑瘫临床症状比较重;CMV感染的脑瘫有37.25％伴有肝功能损害;发育商测定CMV感染的脑瘫90.20％有中重度缺陷,而其他原因所致的脑瘫发育商中重度占52.6％,二者有明显区别(P＜0.05);CMV感染的脑瘫患儿有88.23％运动功能为Ⅱ-Ⅲ级,以中轻度受损为主.结论人巨细胞病毒所致的脑性瘫痪其运动功能大都是中轻度受损,智力发育则明显以中重度缺陷为主,表现出智力受损程度远远大于运动功能受损程度,而其他类型的脑瘫,运动功能受损程度往往大于智力受损程度.同时人巨细胞病毒感染的脑瘫患儿易伴有肝功能损害等多脏器损伤.
목적 대림상증실유거세포병독(CMV)감염소치적뇌성탄탄적환인진행림상특점분석.방법 대51례명학유CMV감염적뇌성탄탄진행상관림상증상분석,조출기특성,병분석기발생적원인.결과 재CMV감염소치적뇌성탄탄적림상증상여기타원인소치적뇌탄상사,단기타원인소치적뇌탄림상증상비교중;CMV감염적뇌탄유37.25％반유간공능손해;발육상측정CMV감염적뇌탄90.20％유중중도결함,이기타원인소치적뇌탄발육상중중도점52.6％,이자유명현구별(P＜0.05);CMV감염적뇌탄환인유88.23％운동공능위Ⅱ-Ⅲ급,이중경도수손위주.결론 인거세포병독소치적뇌성탄탄기운동공능대도시중경도수손,지력발육칙명현이중중도결함위주,표현출지력수손정도원원대우운동공능수손정도,이기타류형적뇌탄,운동공능수손정도왕왕대우지력수손정도.동시인거세포병독감염적뇌탄환인역반유간공능손해등다장기손상.
Objective To Analyze the clinical characteristics of cerebral palsy caused by human cytomegalovirus (CMV) infection.Methods Fifty-one cases of CMV infection were studied by analyzeing related clinical symptoms of cerebral palsy,finding its characteristics,and analyzing its causes by comparing with control group of 50 patients with cerebral palsy caused by other etiologies.Results The clinical symptoms of cerebral palsy caused by CMV infection were similar to those of cerebral palsy caused by other etiologies,however,the clinical symptoms of cerebral palsy caused by other reasons were more severe; 37.25％ of cases with cerebral palsy caused by CMV infection showed damage to liver function.Developmental quotient determination of cerebral palsy caused by CMV infection was 90.20％ which was moderate to severe,whereas that of 52.6％ of cases with cerbral palsy caused by other causes were moderate to severe.There was a significant difference between the two groups with respect to their developmental quotient.The motor function in 88.23％ of patients with cerebral palsy caused by human CMV infection was class Ⅱ-Ⅲ,which was mainly in mild to moderate damage.Conclusions The motor function of cerebral palsy caused by CMV was mostly in the slight to moderat damage,however the mental development obviously was mostly in moderate to severe defects,which showed that the mental damage was much greater than the motor function damage.In patients with cerebral palsy caused by other causes,the degree of motor function damage was higher than the degree of intelligence damage.Besides,the children with cerebral palsy caused by CMV infection were easy to suffer multiple organ injury such as liver damage.