CAJ | 학술논문

Betatrophin是2013年发现的一种由肝脏、白色脂肪组织及褐色脂肪组织分泌的蛋白.其可以显著而特异性地促进胰岛β细胞增生及β细胞数量的增加,从而改善小鼠糖耐量.同时Betatrophin也参与脂代谢.Betatrophin可能成为治疗糖尿病及脂代谢疾病的新靶点.
Betatrophin시2013년발현적일충유간장、백색지방조직급갈색지방조직분비적단백.기가이현저이특이성지촉진이도β세포증생급β세포수량적증가,종이개선소서당내량.동시Betatrophin야삼여지대사.Betatrophin가능성위치료당뇨병급지대사질병적신파점.
Betatrophin,discovered in 2013,is a protein secreted by liver,white adipose tissues,and brown adipose tissues.Betatrophin can improve glucose tolerance in mice by promoting islet β cell proliferation and increasing the number of β cells significantly and specifically.At the same time,Betatrophin is involved in lipid metabolism.Betatrophin may work as the new target for treatment of diabetes and disorders of lipid metabolism.