CAJ | 학술논문

目的：研究结核性胸膜炎运用免疫相关分子联合测定的临床效果。方法：我院选择2012年4月~2014年4月间诊治的100例结核性胸膜炎患者，将其作为观察组。80例非结核性胸腔积液患者，将其作为对照组。对其积液ADA活性、IFN- r含量以及PPD试验阳性率，对结核性胸膜炎的各项指标的特异性和灵敏度进行评价。结果：通过对两组患者进行比较，观察组患者的ADA活性、IFN- r含量以及PPD试验阳性率明显比对照组高，两组患者差异显著，有统计学意义（P<0.05）；结核性胸膜炎运用3项指标联合检测明显比单项检测及其中任何2项的诊断特异度和灵敏度高，差异显著，有统计学意义（P<0.05）。结论：在对结核性胸膜炎诊断的过程中运用多指标联合检测具有很好的临床价值，能够有效的提升诊断阳性率。
목적：연구결핵성흉막염운용면역상관분자연합측정적림상효과。방법：아원선택2012년4월~2014년4월간진치적100례결핵성흉막염환자，장기작위관찰조。80례비결핵성흉강적액환자，장기작위대조조。대기적액ADA활성、IFN- r함량이급PPD시험양성솔，대결핵성흉막염적각항지표적특이성화령민도진행평개。결과：통과대량조환자진행비교，관찰조환자적ADA활성、IFN- r함량이급PPD시험양성솔명현비대조조고，량조환자차이현저，유통계학의의（P<0.05）；결핵성흉막염운용3항지표연합검측명현비단항검측급기중임하2항적진단특이도화령민도고，차이현저，유통계학의의（P<0.05）。결론：재대결핵성흉막염진단적과정중운용다지표연합검측구유흔호적림상개치，능구유효적제승진단양성솔。
To study the clinical effect of tuberculous pleurisy by combined determination of immune related molecules. Methods:select 100 cases in our hospital in patients with tuberculous pleurisy in 2012 April~2014 year in April diagnosis and treatment as the observation group, the. 80 cases of non tuberculous pleural ef-fusion patients, as the control group. The ADA activity, IFN-r content and effusion PPD test positive rate, evaluated the indicators of tuberculous pleurisy specificity and sensitivity. Results:the two groups of patients were compared in the observation group, ADA activity, IFN-r content and PPD test positive rate was significantly higher than the control group, the differences between the two groups were significant, with statistical significance (P<0.05);tuberculous pleurisy by combined detec-tion of 3 indexes were compared with single detection and any of these 2 items of diagnosis specificity and high sensitivity, significant difference was statistically sig-nificant (P<0.05). Conclusion:the use of multiple combined detection indexes in diagnosis of tuberculous pleurisy in clinical value is very good, can effectively im-prove the diagnostic positive rate.